rs1519548

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0366 (10940/29822,GnomAD)
C==0375 (10924/29118,TOPMED)
C==0308 (1542/5008,1000G)
C==0428 (1649/3854,ALSPAC)
C==0415 (1540/3708,TWINSUK)
chr4:141609456 (GRCh38.p7) (4q31.21)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.141609456C>T
GRCh37.p13 chr 4NC_000004.11:g.142530609C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.371T=0.629
1000GenomesAmericanSub694C=0.350T=0.650
1000GenomesEast AsianSub1008C=0.055T=0.945
1000GenomesEuropeSub1006C=0.433T=0.567
1000GenomesGlobalStudy-wide5008C=0.308T=0.692
1000GenomesSouth AsianSub978C=0.320T=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.428T=0.572
The Genome Aggregation DatabaseAfricanSub8660C=0.365T=0.635
The Genome Aggregation DatabaseAmericanSub838C=0.310T=0.690
The Genome Aggregation DatabaseEast AsianSub1616C=0.039T=0.961
The Genome Aggregation DatabaseEuropeSub18406C=0.399T=0.600
The Genome Aggregation DatabaseGlobalStudy-wide29822C=0.366T=0.633
The Genome Aggregation DatabaseOtherSub302C=0.360T=0.640
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.375T=0.624
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.415T=0.585
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15195480.000288alcohol dependence20201924

eQTL of rs1519548 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1519548 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4142573430142573920E06842821
chr4142573430142573920E07442821
chr4142574074142574175E07443465


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4142556973142558580E06726364
chr4142556973142558580E06826364
chr4142558619142558695E06828010
chr4142556973142558580E06926364
chr4142558619142558695E06928010
chr4142556973142558580E07126364
chr4142558619142558695E07128010
chr4142556973142558580E07226364
chr4142556973142558580E07326364
chr4142556973142558580E07426364
chr4142556973142558580E08226364