rs1523145

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0471 (14069/29834,GnomAD)
C=0484 (14113/29118,TOPMED)
T==0459 (2301/5008,1000G)
T==0460 (1772/3854,ALSPAC)
T==0473 (1753/3708,TWINSUK)
chr4:31862267 (GRCh38.p7) (4p15.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.31862267T>C
GRCh37.p13 chr 4NC_000004.11:g.31863889T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.511C=0.489
1000GenomesAmericanSub694T=0.530C=0.470
1000GenomesEast AsianSub1008T=0.218C=0.782
1000GenomesEuropeSub1006T=0.499C=0.501
1000GenomesGlobalStudy-wide5008T=0.459C=0.541
1000GenomesSouth AsianSub978T=0.540C=0.460
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.460C=0.540
The Genome Aggregation DatabaseAfricanSub8674T=0.518C=0.482
The Genome Aggregation DatabaseAmericanSub836T=0.500C=0.500
The Genome Aggregation DatabaseEast AsianSub1590T=0.209C=0.791
The Genome Aggregation DatabaseEuropeSub18432T=0.471C=0.528
The Genome Aggregation DatabaseGlobalStudy-wide29834T=0.471C=0.528
The Genome Aggregation DatabaseOtherSub302T=0.450C=0.550
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.515C=0.484
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.473C=0.527
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15231450.00084alcohol dependence20201924

eQTL of rs1523145 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1523145 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.