rs1534165

Homo sapiens
T>C
SRPRB : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0127 (3818/29988,GnomAD)
C=0117 (3432/29118,TOPMED)
C=0209 (1045/5008,1000G)
C=0139 (536/3854,ALSPAC)
C=0149 (553/3708,TWINSUK)
chr3:133818073 (GRCh38.p7) (3q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
87 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.133818073T>C
GRCh37.p13 chr 3NC_000003.11:g.133536917T>C

Gene: SRPRB, SRP receptor beta subunit(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SRPRB transcriptNM_021203.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.984C=0.016
1000GenomesAmericanSub694T=0.830C=0.170
1000GenomesEast AsianSub1008T=0.562C=0.438
1000GenomesEuropeSub1006T=0.827C=0.173
1000GenomesGlobalStudy-wide5008T=0.791C=0.209
1000GenomesSouth AsianSub978T=0.700C=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.861C=0.139
The Genome Aggregation DatabaseAfricanSub8734T=0.962C=0.038
The Genome Aggregation DatabaseAmericanSub838T=0.790C=0.210
The Genome Aggregation DatabaseEast AsianSub1616T=0.580C=0.420
The Genome Aggregation DatabaseEuropeSub18502T=0.860C=0.139
The Genome Aggregation DatabaseGlobalStudy-wide29988T=0.872C=0.127
The Genome Aggregation DatabaseOtherSub298T=0.840C=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.882C=0.117
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.851C=0.149
PMID Title Author Journal
21665994Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.Kutalik ZHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs15341651.15E-07alcohol consumption21665994

eQTL of rs1534165 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1534165 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3133562885133562960E06725968
chr3133573215133573347E06736298
chr3133573885133574171E06736968
chr3133574725133574824E06737808
chr3133575303133575377E06738386
chr3133584047133584242E06747130
chr3133572273133572376E06835356
chr3133572430133572579E06835513
chr3133572588133572638E06835671
chr3133573215133573347E06836298
chr3133573885133574171E06836968
chr3133574725133574824E06837808
chr3133575303133575377E06838386
chr3133584047133584242E06847130
chr3133540603133541021E0693686
chr3133541191133541245E0694274
chr3133572273133572376E06935356
chr3133572430133572579E06935513
chr3133572588133572638E06935671
chr3133573215133573347E06936298
chr3133573885133574171E06936968
chr3133574725133574824E06937808
chr3133575303133575377E06938386
chr3133584047133584242E06947130
chr3133547093133547193E07010176
chr3133547516133547745E07010599
chr3133547924133548172E07011007
chr3133572273133572376E07035356
chr3133572430133572579E07035513
chr3133572588133572638E07035671
chr3133573215133573347E07036298
chr3133573885133574171E07036968
chr3133574725133574824E07037808
chr3133575303133575377E07038386
chr3133540337133540417E0713420
chr3133572273133572376E07135356
chr3133572430133572579E07135513
chr3133572588133572638E07135671
chr3133573215133573347E07136298
chr3133573885133574171E07136968
chr3133574725133574824E07137808
chr3133582903133583150E07145986
chr3133584047133584242E07147130
chr3133573215133573347E07236298
chr3133573885133574171E07236968
chr3133574725133574824E07237808
chr3133582298133582380E07245381
chr3133584047133584242E07247130
chr3133540006133540074E0733089
chr3133540337133540417E0733420
chr3133540603133541021E0733686
chr3133541035133541081E0734118
chr3133541191133541245E0734274
chr3133572273133572376E07335356
chr3133573215133573347E07336298
chr3133573885133574171E07336968
chr3133574725133574824E07337808
chr3133575303133575377E07338386
chr3133584047133584242E07347130
chr3133540006133540074E0743089
chr3133540337133540417E0743420
chr3133540603133541021E0743686
chr3133541035133541081E0744118
chr3133541191133541245E0744274
chr3133541431133541497E0744514
chr3133541623133541762E0744706
chr3133541910133541964E0744993
chr3133572430133572579E07435513
chr3133572588133572638E07435671
chr3133573215133573347E07436298
chr3133573885133574171E07436968
chr3133574725133574824E07437808
chr3133526132133526214E081-10703
chr3133572273133572376E08135356
chr3133573215133573347E08136298
chr3133573885133574171E08136968
chr3133574725133574824E08137808
chr3133547516133547745E08210599
chr3133547924133548172E08211007
chr3133548284133548391E08211367
chr3133572273133572376E08235356
chr3133572430133572579E08235513
chr3133572588133572638E08235671
chr3133573215133573347E08236298
chr3133573885133574171E08236968
chr3133574725133574824E08237808
chr3133575303133575377E08238386










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3133524082133525550E067-11367
chr3133525588133525634E067-11283
chr3133524082133525550E068-11367
chr3133525588133525634E068-11283
chr3133524082133525550E069-11367
chr3133524082133525550E070-11367
chr3133525588133525634E070-11283
chr3133524082133525550E071-11367
chr3133525588133525634E071-11283
chr3133524082133525550E072-11367
chr3133525588133525634E072-11283
chr3133524082133525550E073-11367
chr3133525588133525634E073-11283
chr3133524082133525550E074-11367
chr3133525588133525634E074-11283
chr3133524082133525550E081-11367
chr3133525588133525634E081-11283
chr3133524082133525550E082-11367
chr3133525588133525634E082-11283