rs1534166

Homo sapiens
A>G
SRPRB : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0280 (8391/29950,GnomAD)
G=0281 (8194/29118,TOPMED)
G=0251 (1259/5008,1000G)
G=0279 (1075/3854,ALSPAC)
G=0283 (1051/3708,TWINSUK)
chr3:133818223 (GRCh38.p7) (3q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
87 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.133818223A>G
GRCh37.p13 chr 3NC_000003.11:g.133537067A>G

Gene: SRPRB, SRP receptor beta subunit(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SRPRB transcriptNM_021203.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.706G=0.294
1000GenomesAmericanSub694A=0.780G=0.220
1000GenomesEast AsianSub1008A=0.785G=0.215
1000GenomesEuropeSub1006A=0.720G=0.280
1000GenomesGlobalStudy-wide5008A=0.749G=0.251
1000GenomesSouth AsianSub978A=0.780G=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.721G=0.279
The Genome Aggregation DatabaseAfricanSub8696A=0.699G=0.301
The Genome Aggregation DatabaseAmericanSub838A=0.820G=0.180
The Genome Aggregation DatabaseEast AsianSub1620A=0.796G=0.204
The Genome Aggregation DatabaseEuropeSub18496A=0.719G=0.280
The Genome Aggregation DatabaseGlobalStudy-wide29950A=0.719G=0.280
The Genome Aggregation DatabaseOtherSub300A=0.660G=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.718G=0.281
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.717G=0.283
PMID Title Author Journal
21665994Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.Kutalik ZHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs15341662E-17alcohol consumption (transferrin glycosylation)21665994

eQTL of rs1534166 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1534166 in Fetal Brain

Probe ID Position Gene beta p-value
cg11941060chr3:1335025640.05387196412614936.8859e-9

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3133562885133562960E06725818
chr3133573215133573347E06736148
chr3133573885133574171E06736818
chr3133574725133574824E06737658
chr3133575303133575377E06738236
chr3133584047133584242E06746980
chr3133572273133572376E06835206
chr3133572430133572579E06835363
chr3133572588133572638E06835521
chr3133573215133573347E06836148
chr3133573885133574171E06836818
chr3133574725133574824E06837658
chr3133575303133575377E06838236
chr3133584047133584242E06846980
chr3133540603133541021E0693536
chr3133541191133541245E0694124
chr3133572273133572376E06935206
chr3133572430133572579E06935363
chr3133572588133572638E06935521
chr3133573215133573347E06936148
chr3133573885133574171E06936818
chr3133574725133574824E06937658
chr3133575303133575377E06938236
chr3133584047133584242E06946980
chr3133547093133547193E07010026
chr3133547516133547745E07010449
chr3133547924133548172E07010857
chr3133572273133572376E07035206
chr3133572430133572579E07035363
chr3133572588133572638E07035521
chr3133573215133573347E07036148
chr3133573885133574171E07036818
chr3133574725133574824E07037658
chr3133575303133575377E07038236
chr3133540337133540417E0713270
chr3133572273133572376E07135206
chr3133572430133572579E07135363
chr3133572588133572638E07135521
chr3133573215133573347E07136148
chr3133573885133574171E07136818
chr3133574725133574824E07137658
chr3133582903133583150E07145836
chr3133584047133584242E07146980
chr3133573215133573347E07236148
chr3133573885133574171E07236818
chr3133574725133574824E07237658
chr3133582298133582380E07245231
chr3133584047133584242E07246980
chr3133540006133540074E0732939
chr3133540337133540417E0733270
chr3133540603133541021E0733536
chr3133541035133541081E0733968
chr3133541191133541245E0734124
chr3133572273133572376E07335206
chr3133573215133573347E07336148
chr3133573885133574171E07336818
chr3133574725133574824E07337658
chr3133575303133575377E07338236
chr3133584047133584242E07346980
chr3133540006133540074E0742939
chr3133540337133540417E0743270
chr3133540603133541021E0743536
chr3133541035133541081E0743968
chr3133541191133541245E0744124
chr3133541431133541497E0744364
chr3133541623133541762E0744556
chr3133541910133541964E0744843
chr3133572430133572579E07435363
chr3133572588133572638E07435521
chr3133573215133573347E07436148
chr3133573885133574171E07436818
chr3133574725133574824E07437658
chr3133526132133526214E081-10853
chr3133572273133572376E08135206
chr3133573215133573347E08136148
chr3133573885133574171E08136818
chr3133574725133574824E08137658
chr3133547516133547745E08210449
chr3133547924133548172E08210857
chr3133548284133548391E08211217
chr3133572273133572376E08235206
chr3133572430133572579E08235363
chr3133572588133572638E08235521
chr3133573215133573347E08236148
chr3133573885133574171E08236818
chr3133574725133574824E08237658
chr3133575303133575377E08238236










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3133524082133525550E067-11517
chr3133525588133525634E067-11433
chr3133524082133525550E068-11517
chr3133525588133525634E068-11433
chr3133524082133525550E069-11517
chr3133524082133525550E070-11517
chr3133525588133525634E070-11433
chr3133524082133525550E071-11517
chr3133525588133525634E071-11433
chr3133524082133525550E072-11517
chr3133525588133525634E072-11433
chr3133524082133525550E073-11517
chr3133525588133525634E073-11433
chr3133524082133525550E074-11517
chr3133525588133525634E074-11433
chr3133524082133525550E081-11517
chr3133525588133525634E081-11433
chr3133524082133525550E082-11517
chr3133525588133525634E082-11433