rs1536701

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0253 (7586/29936,GnomAD)
A=0262 (7652/29118,TOPMED)
A=0231 (1156/5008,1000G)
A=0237 (914/3854,ALSPAC)
A=0231 (856/3708,TWINSUK)
chr6:41902186 (GRCh38.p7) (6p21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
63 Enhancers around
30 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.41902186G>A
GRCh37.p13 chr 6NC_000006.11:g.41869924G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.663A=0.337
1000GenomesAmericanSub694G=0.830A=0.170
1000GenomesEast AsianSub1008G=0.842A=0.158
1000GenomesEuropeSub1006G=0.764A=0.236
1000GenomesGlobalStudy-wide5008G=0.769A=0.231
1000GenomesSouth AsianSub978G=0.800A=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.763A=0.237
The Genome Aggregation DatabaseAfricanSub8708G=0.702A=0.298
The Genome Aggregation DatabaseAmericanSub836G=0.830A=0.170
The Genome Aggregation DatabaseEast AsianSub1616G=0.819A=0.181
The Genome Aggregation DatabaseEuropeSub18474G=0.756A=0.243
The Genome Aggregation DatabaseGlobalStudy-wide29936G=0.746A=0.253
The Genome Aggregation DatabaseOtherSub302G=0.780A=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.737A=0.262
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.769A=0.231
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs15367010.000928nicotine dependence17158188

eQTL of rs1536701 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1536701 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr64185510141855212E067-14712
chr64185540041855489E067-14435
chr64186122841861328E067-8596
chr64186138541861530E067-8394
chr64190381841904578E06733894
chr64190534841905501E06735424
chr64190556841905726E06735644
chr64190644741906530E06736523
chr64187730241877373E0687378
chr64190381841904578E06833894
chr64190496341905013E06835039
chr64190534841905501E06835424
chr64190556841905726E06835644
chr64190644741906530E06836523
chr64185510141855212E069-14712
chr64186138541861530E069-8394
chr64187730241877373E0697378
chr64190381841904578E06933894
chr64190469441904745E06934770
chr64190644741906530E06936523
chr64185510141855212E070-14712
chr64185540041855489E070-14435
chr64186098641861071E071-8853
chr64186112641861182E071-8742
chr64186122841861328E071-8596
chr64186138541861530E071-8394
chr64187730241877373E0717378
chr64189075741890838E07120833
chr64190381841904578E07133894
chr64190469441904745E07134770
chr64190496341905013E07135039
chr64190644741906530E07136523
chr64186122841861328E072-8596
chr64186138541861530E072-8394
chr64187730241877373E0727378
chr64190381841904578E07233894
chr64190644741906530E07236523
chr64186122841861328E073-8596
chr64186138541861530E073-8394
chr64188220341882378E07312279
chr64189075741890838E07320833
chr64190381841904578E07333894
chr64190469441904745E07334770
chr64190496341905013E07335039
chr64190534841905501E07335424
chr64190556841905726E07335644
chr64190644741906530E07336523
chr64185510141855212E074-14712
chr64185540041855489E074-14435
chr64187730241877373E0747378
chr64190381841904578E07433894
chr64190469441904745E07434770
chr64190644741906530E07436523
chr64186098641861071E081-8853
chr64186112641861182E081-8742
chr64189075741890838E08120833
chr64189157441891670E08121650
chr64185284841853002E082-16922
chr64185421741854269E082-15655
chr64185510141855212E082-14712
chr64189075741890838E08220833
chr64189157441891670E08221650
chr64190644741906530E08236523










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr64186209641864047E067-5877
chr64188820541888337E06718281
chr64188840241889795E06718478
chr64186209641864047E068-5877
chr64188820541888337E06818281
chr64188840241889795E06818478
chr64186209641864047E069-5877
chr64188820541888337E06918281
chr64188840241889795E06918478
chr64186209641864047E070-5877
chr64188820541888337E07018281
chr64188840241889795E07018478
chr64186209641864047E071-5877
chr64188820541888337E07118281
chr64188840241889795E07118478
chr64186209641864047E072-5877
chr64188820541888337E07218281
chr64188840241889795E07218478
chr64186209641864047E073-5877
chr64188820541888337E07318281
chr64188840241889795E07318478
chr64186209641864047E074-5877
chr64188820541888337E07418281
chr64188840241889795E07418478
chr64186209641864047E081-5877
chr64188820541888337E08118281
chr64188840241889795E08118478
chr64186209641864047E082-5877
chr64188820541888337E08218281
chr64188840241889795E08218478