rs1541918

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0106 (3182/29952,GnomAD)
A=0113 (3299/29118,TOPMED)
A=0109 (544/5008,1000G)
A=0120 (464/3854,ALSPAC)
A=0128 (475/3708,TWINSUK)
chr5:172544483 (GRCh38.p7) (5q35.1)
AD
GWASdb2
1   publication(s)
See rs on genome
221 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.172544483C>A
GRCh37.p13 chr 5NC_000005.9:g.171971486C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.926A=0.074
1000GenomesAmericanSub694C=0.880A=0.120
1000GenomesEast AsianSub1008C=0.896A=0.104
1000GenomesEuropeSub1006C=0.883A=0.117
1000GenomesGlobalStudy-wide5008C=0.891A=0.109
1000GenomesSouth AsianSub978C=0.860A=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.880A=0.120
The Genome Aggregation DatabaseAfricanSub8710C=0.906A=0.094
The Genome Aggregation DatabaseAmericanSub838C=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1620C=0.893A=0.107
The Genome Aggregation DatabaseEuropeSub18482C=0.888A=0.111
The Genome Aggregation DatabaseGlobalStudy-wide29952C=0.893A=0.106
The Genome Aggregation DatabaseOtherSub302C=0.860A=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.886A=0.113
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.872A=0.128
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs15419181.1E-06alcoholism (heaviness of drinking)21529783

eQTL of rs1541918 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1541918 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5171923979171924383E067-47103
chr5171924567171924607E067-46879
chr5171960718171961178E067-10308
chr5171971760171972178E067274
chr5171972394171972444E067908
chr5171975311171975450E0673825
chr5171975585171975682E0674099
chr5171975900171975981E0674414
chr5171976025171976120E0674539
chr5171977586171977928E0676100
chr5171983919171984678E06712433
chr5171984687171984706E06713201
chr5171984819171984995E06713333
chr5172002400172002517E06730914
chr5172002683172002771E06731197
chr5172002864172002914E06731378
chr5172002980172003173E06731494
chr5172003210172003496E06731724
chr5172004426172004540E06732940
chr5172004747172004799E06733261
chr5171923979171924383E068-47103
chr5171924567171924607E068-46879
chr5171935884171936027E068-35459
chr5171936390171936783E068-34703
chr5171975311171975450E0683825
chr5171975585171975682E0684099
chr5171975900171975981E0684414
chr5171976025171976120E0684539
chr5171976288171976367E0684802
chr5171976475171976564E0684989
chr5171984687171984706E06813201
chr5171984819171984995E06813333
chr5171985488171985624E06814002
chr5171985653171985697E06814167
chr5171985821171986826E06814335
chr5172000665172000962E06829179
chr5172001063172001113E06829577
chr5172001158172001208E06829672
chr5172001566172002239E06830080
chr5172002266172002341E06830780
chr5172002400172002517E06830914
chr5172002683172002771E06831197
chr5172002864172002914E06831378
chr5172002980172003173E06831494
chr5172003210172003496E06831724
chr5172004426172004540E06832940
chr5172004747172004799E06833261
chr5171923863171923971E069-47515
chr5171923979171924383E069-47103
chr5171924567171924607E069-46879
chr5171960458171960636E069-10850
chr5171960718171961178E069-10308
chr5171961332171961461E069-10025
chr5171970961171971039E069-447
chr5171971760171972178E069274
chr5171972394171972444E069908
chr5171972497171972834E0691011
chr5171972891171972969E0691405
chr5171973027171973077E0691541
chr5171973358171973408E0691872
chr5171975311171975450E0693825
chr5171975585171975682E0694099
chr5171975900171975981E0694414
chr5171976025171976120E0694539
chr5171976288171976367E0694802
chr5171976475171976564E0694989
chr5171976898171977042E0695412
chr5171977190171977332E0695704
chr5171977586171977928E0696100
chr5171981013171981158E0699527
chr5171983774171983849E06912288
chr5171983919171984678E06912433
chr5172001158172001208E06929672
chr5172001566172002239E06930080
chr5172002266172002341E06930780
chr5172002400172002517E06930914
chr5172002683172002771E06931197
chr5172002864172002914E06931378
chr5172002980172003173E06931494
chr5172003210172003496E06931724
chr5172004426172004540E06932940
chr5172004747172004799E06933261
chr5171971760171972178E070274
chr5171981548171981602E07010062
chr5171981646171981921E07010160
chr5171981968171982075E07010482
chr5171982134171982200E07010648
chr5171923863171923971E071-47515
chr5171923979171924383E071-47103
chr5171924567171924607E071-46879
chr5171924942171924992E071-46494
chr5171960458171960636E071-10850
chr5171960718171961178E071-10308
chr5171961332171961461E071-10025
chr5171971760171972178E071274
chr5171972394171972444E071908
chr5171975311171975450E0713825
chr5171975585171975682E0714099
chr5171975900171975981E0714414
chr5171976025171976120E0714539
chr5171976288171976367E0714802
chr5171981013171981158E0719527
chr5171981548171981602E07110062
chr5171981646171981921E07110160
chr5171981968171982075E07110482
chr5171983774171983849E07112288
chr5171983919171984678E07112433
chr5171984687171984706E07113201
chr5171984819171984995E07113333
chr5172001566172002239E07130080
chr5172002266172002341E07130780
chr5172002400172002517E07130914
chr5172002683172002771E07131197
chr5172002864172002914E07131378
chr5172002980172003173E07131494
chr5172003210172003496E07131724
chr5172004426172004540E07132940
chr5172004747172004799E07133261
chr5171923863171923971E072-47515
chr5171923979171924383E072-47103
chr5171924567171924607E072-46879
chr5171960458171960636E072-10850
chr5171960718171961178E072-10308
chr5171961332171961461E072-10025
chr5171971233171971370E072-116
chr5171971760171972178E072274
chr5171972394171972444E072908
chr5171972497171972834E0721011
chr5171972891171972969E0721405
chr5171973027171973077E0721541
chr5171973358171973408E0721872
chr5171975311171975450E0723825
chr5171975585171975682E0724099
chr5171975900171975981E0724414
chr5171976025171976120E0724539
chr5171983774171983849E07212288
chr5171983919171984678E07212433
chr5172001063172001113E07229577
chr5172001158172001208E07229672
chr5172001566172002239E07230080
chr5172002266172002341E07230780
chr5172002400172002517E07230914
chr5172002683172002771E07231197
chr5172002864172002914E07231378
chr5172002980172003173E07231494
chr5172003210172003496E07231724
chr5172004426172004540E07232940
chr5172004747172004799E07233261
chr5171923863171923971E073-47515
chr5171923979171924383E073-47103
chr5171924567171924607E073-46879
chr5171961332171961461E073-10025
chr5171972394171972444E073908
chr5171975311171975450E0733825
chr5171975585171975682E0734099
chr5171975900171975981E0734414
chr5171976025171976120E0734539
chr5171983919171984678E07312433
chr5171984687171984706E07313201
chr5172001063172001113E07329577
chr5172001158172001208E07329672
chr5172001566172002239E07330080
chr5172002266172002341E07330780
chr5172002400172002517E07330914
chr5172002683172002771E07331197
chr5172002864172002914E07331378
chr5172002980172003173E07331494
chr5172003210172003496E07331724
chr5171923979171924383E074-47103
chr5171924567171924607E074-46879
chr5171971760171972178E074274
chr5171972394171972444E074908
chr5171975311171975450E0743825
chr5171975585171975682E0744099
chr5171975900171975981E0744414
chr5171976025171976120E0744539
chr5171977586171977928E0746100
chr5171983774171983849E07412288
chr5171983919171984678E07412433
chr5172001063172001113E07429577
chr5172002683172002771E07431197
chr5172002864172002914E07431378
chr5172002980172003173E07431494
chr5172003210172003496E07431724
chr5172004747172004799E07433261
chr5171951578171951805E081-19681
chr5171951926171952008E081-19478
chr5171960458171960636E081-10850
chr5171960718171961178E081-10308
chr5171961332171961461E081-10025
chr5171983774171983849E08112288
chr5171998198171998337E08126712
chr5171998486171998624E08127000
chr5171999841171999920E08128355
chr5172000041172000248E08128555
chr5172000339172000418E08128853
chr5172000665172000962E08129179
chr5172001063172001113E08129577
chr5172001158172001208E08129672
chr5172001566172002239E08130080
chr5172002266172002341E08130780
chr5172002400172002517E08130914
chr5172002683172002771E08131197
chr5172002864172002914E08131378
chr5172002980172003173E08131494
chr5172006806172006856E08135320
chr5172007236172007290E08135750
chr5172013194172013482E08141708
chr5172013532172013671E08142046
chr5172013685172013772E08142199
chr5172013787172013913E08142301
chr5171971760171972178E082274
chr5171972394171972444E082908
chr5172000665172000962E08229179
chr5172001063172001113E08229577
chr5172001158172001208E08229672
chr5172002400172002517E08230914
chr5172002683172002771E08231197
chr5172002864172002914E08231378
chr5172002980172003173E08231494
chr5172003210172003496E08231724