rs1567887

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0344 (10321/29932,GnomAD)
T=0331 (9644/29118,TOPMED)
T=0423 (2117/5008,1000G)
T=0351 (1351/3854,ALSPAC)
T=0371 (1375/3708,TWINSUK)
chr15:32007750 (GRCh38.p7) (15q13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
50 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.32007750C>T
GRCh37.p13 chr 15NC_000015.9:g.32299953C>T
GRCh38.p7 chr 15 fix patch HG2139_PATCHNW_011332701.1:g.4180422C>T
GRCh38.p7 chr 15 alt locus HSCHR15_4_CTG8NT_187660.1:g.4292874C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.689T=0.311
1000GenomesAmericanSub694C=0.510T=0.490
1000GenomesEast AsianSub1008C=0.560T=0.440
1000GenomesEuropeSub1006C=0.656T=0.344
1000GenomesGlobalStudy-wide5008C=0.577T=0.423
1000GenomesSouth AsianSub978C=0.410T=0.590
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.649T=0.351
The Genome Aggregation DatabaseAfricanSub8706C=0.691T=0.309
The Genome Aggregation DatabaseAmericanSub838C=0.550T=0.450
The Genome Aggregation DatabaseEast AsianSub1614C=0.524T=0.476
The Genome Aggregation DatabaseEuropeSub18472C=0.655T=0.344
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.655T=0.344
The Genome Aggregation DatabaseOtherSub302C=0.610T=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.668T=0.331
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.629T=0.371
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15678870.00036alcohol dependence(early age of onset)20201924
rs15678870.00044alcohol dependence20201924

eQTL of rs1567887 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1567887 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr153227046032270791E068-29162
chr153226665832268009E070-31944
chr153227734632277488E070-22465
chr153227770432277999E070-21954
chr153227821732278359E070-21594
chr153232097232321088E07021019
chr153232525232325962E07025299
chr153232525232325962E07425299
chr153226665832268009E081-31944
chr153226807432268450E082-31503





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr153232116332323031E06721210
chr153232304332323314E06723090
chr153232332132323453E06723368
chr153232345832323508E06723505
chr153232355232323606E06723599
chr153232116332323031E06821210
chr153232304332323314E06823090
chr153232332132323453E06823368
chr153232345832323508E06823505
chr153232355232323606E06823599
chr153232116332323031E06921210
chr153232304332323314E06923090
chr153232332132323453E06923368
chr153232345832323508E06923505
chr153232355232323606E06923599
chr153232116332323031E07021210
chr153232304332323314E07023090
chr153232332132323453E07023368
chr153232345832323508E07023505
chr153232355232323606E07023599
chr153232360932323659E07023656
chr153232376332323832E07023810
chr153232116332323031E07121210
chr153232304332323314E07123090
chr153232332132323453E07123368
chr153232345832323508E07123505
chr153232355232323606E07123599
chr153232116332323031E07221210
chr153232304332323314E07223090
chr153232332132323453E07223368
chr153232345832323508E07223505
chr153232355232323606E07223599
chr153232360932323659E07223656
chr153232376332323832E07223810
chr153232386132323968E07223908
chr153232116332323031E07321210
chr153232304332323314E07323090
chr153232332132323453E07323368
chr153232345832323508E07323505
chr153232116332323031E07421210
chr153232304332323314E07423090
chr153232332132323453E07423368
chr153232116332323031E08121210
chr153232116332323031E08221210
chr153232304332323314E08223090
chr153232332132323453E08223368
chr153232345832323508E08223505
chr153232355232323606E08223599
chr153232360932323659E08223656
chr153232376332323832E08223810