rs1570589

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0317 (9341/29424,GnomAD)
G=0282 (8236/29118,TOPMED)
G=0310 (1551/5008,1000G)
G=0249 (961/3854,ALSPAC)
G=0262 (972/3708,TWINSUK)
chr9:114112075 (GRCh38.p7) (9q32)
AD
GWASdb2
1   publication(s)
See rs on genome
138 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.114112075A>G
GRCh37.p13 chr 9NC_000009.11:g.116874355A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.681G=0.319
1000GenomesAmericanSub694A=0.720G=0.280
1000GenomesEast AsianSub1008A=0.610G=0.390
1000GenomesEuropeSub1006A=0.730G=0.270
1000GenomesGlobalStudy-wide5008A=0.690G=0.310
1000GenomesSouth AsianSub978A=0.720G=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.751G=0.249
The Genome Aggregation DatabaseAfricanSub8606A=0.683G=0.317
The Genome Aggregation DatabaseAmericanSub796A=0.720G=0.280
The Genome Aggregation DatabaseEast AsianSub1606A=0.608G=0.392
The Genome Aggregation DatabaseEuropeSub18116A=0.684G=0.315
The Genome Aggregation DatabaseGlobalStudy-wide29424A=0.682G=0.317
The Genome Aggregation DatabaseOtherSub300A=0.880G=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.717G=0.282
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.738G=0.262
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15705890.00061alcohol dependence20201924

eQTL of rs1570589 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1570589 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9116875940116876054E0671585
chr9116879600116879650E0675245
chr9116879838116879888E0675483
chr9116879917116880152E0675562
chr9116880168116881047E0675813
chr9116881286116881363E0676931
chr9116881373116881460E0677018
chr9116902049116902099E06727694
chr9116902176116902240E06727821
chr9116902339116902536E06727984
chr9116902542116902596E06728187
chr9116834463116834885E068-39470
chr9116834893116835212E068-39143
chr9116835257116835336E068-39019
chr9116874896116874948E068541
chr9116875384116875897E0681029
chr9116875940116876054E0681585
chr9116878717116878788E0684362
chr9116878813116878930E0684458
chr9116879600116879650E0685245
chr9116879838116879888E0685483
chr9116879917116880152E0685562
chr9116880168116881047E0685813
chr9116881286116881363E0686931
chr9116881373116881460E0687018
chr9116881541116881734E0687186
chr9116900892116900942E06826537
chr9116901019116901267E06826664
chr9116901286116901365E06826931
chr9116901428116901697E06827073
chr9116901711116901871E06827356
chr9116902049116902099E06827694
chr9116902176116902240E06827821
chr9116902339116902536E06827984
chr9116902542116902596E06828187
chr9116902812116902906E06828457
chr9116913905116914091E06839550
chr9116914112116914166E06839757
chr9116914286116914361E06839931
chr9116914483116914594E06840128
chr9116834191116834241E069-40114
chr9116834463116834885E069-39470
chr9116834893116835212E069-39143
chr9116878717116878788E0694362
chr9116878813116878930E0694458
chr9116879600116879650E0695245
chr9116879838116879888E0695483
chr9116879917116880152E0695562
chr9116881286116881363E0696931
chr9116881373116881460E0697018
chr9116881541116881734E0697186
chr9116881742116881835E0697387
chr9116892337116892665E06917982
chr9116901711116901871E06927356
chr9116902049116902099E06927694
chr9116902176116902240E06927821
chr9116902339116902536E06927984
chr9116902542116902596E06928187
chr9116902812116902906E06928457
chr9116903002116903052E06928647
chr9116903125116903574E06928770
chr9116903834116903874E06929479
chr9116903971116904049E06929616
chr9116904079116904678E06929724
chr9116834893116835212E070-39143
chr9116835257116835336E070-39019
chr9116859328116859522E070-14833
chr9116880168116881047E0705813
chr9116870069116871468E071-2887
chr9116875940116876054E0711585
chr9116877941116878574E0713586
chr9116878717116878788E0714362
chr9116878813116878930E0714458
chr9116879600116879650E0715245
chr9116879838116879888E0715483
chr9116879917116880152E0715562
chr9116880168116881047E0715813
chr9116881286116881363E0716931
chr9116881373116881460E0717018
chr9116881541116881734E0717186
chr9116881742116881835E0717387
chr9116902049116902099E07127694
chr9116902176116902240E07127821
chr9116902339116902536E07127984
chr9116902542116902596E07128187
chr9116870069116871468E072-2887
chr9116875384116875897E0721029
chr9116875940116876054E0721585
chr9116877941116878574E0723586
chr9116878717116878788E0724362
chr9116878813116878930E0724458
chr9116879600116879650E0725245
chr9116879838116879888E0725483
chr9116879917116880152E0725562
chr9116880168116881047E0725813
chr9116875940116876054E0731585
chr9116880168116881047E0735813
chr9116881286116881363E0736931
chr9116881373116881460E0737018
chr9116881541116881734E0737186
chr9116881742116881835E0737387
chr9116902339116902536E07327984
chr9116902542116902596E07328187
chr9116902812116902906E07328457
chr9116903002116903052E07328647
chr9116903125116903574E07328770
chr9116903834116903874E07329479
chr9116903971116904049E07329616
chr9116844124116845318E074-29037
chr9116870069116871468E074-2887
chr9116875384116875897E0741029
chr9116875940116876054E0741585
chr9116877941116878574E0743586
chr9116878717116878788E0744362
chr9116878813116878930E0744458
chr9116879600116879650E0745245
chr9116879838116879888E0745483
chr9116879917116880152E0745562
chr9116880168116881047E0745813
chr9116881286116881363E0746931
chr9116881373116881460E0747018
chr9116881541116881734E0747186
chr9116881742116881835E0747387
chr9116881879116882199E0747524
chr9116901019116901267E07426664
chr9116901286116901365E07426931
chr9116901428116901697E07427073
chr9116901711116901871E07427356
chr9116902049116902099E07427694
chr9116902176116902240E07427821
chr9116902339116902536E07427984
chr9116902542116902596E07428187
chr9116902812116902906E07428457
chr9116903834116903874E07429479
chr9116903971116904049E07429616
chr9116904079116904678E07429724
chr9116859328116859522E081-14833
chr9116880168116881047E0815813









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9116918147116918263E06743792
chr9116918297116918532E06743942
chr9116918584116919814E06744229
chr9116915920116918054E06841565
chr9116918147116918263E06843792
chr9116918297116918532E06843942
chr9116918584116919814E06844229
chr9116918147116918263E06943792
chr9116918297116918532E06943942
chr9116918584116919814E06944229
chr9116918147116918263E07043792
chr9116918297116918532E07043942
chr9116918584116919814E07044229
chr9116918147116918263E07143792
chr9116918297116918532E07143942
chr9116859703116862217E072-12138
chr9116918147116918263E07243792
chr9116918297116918532E07243942
chr9116918584116919814E07244229
chr9116915920116918054E07341565
chr9116918147116918263E07343792
chr9116918297116918532E07343942
chr9116918584116919814E07344229
chr9116918147116918263E07443792
chr9116918297116918532E07443942
chr9116918584116919814E07444229
chr9116918147116918263E08243792
chr9116918297116918532E08243942
chr9116918584116919814E08244229