SNP Detail Info-rs1577822

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0400 (11869/29672,GnomAD)
G=0348 (10142/29118,TOPMED)
G=0437 (2188/5008,1000G)
G=0458 (1764/3854,ALSPAC)
G=0472 (1749/3708,TWINSUK)

Position: chr6:62875235 (GRCh38.p7) (6q12)

Phenotype: OD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.62875235T>G
GRCh37.p13 chr 6	NC_000006.11:g.63585140T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.833	G=0.167
1000Genomes	American	Sub	694	T=0.470	G=0.530
1000Genomes	East Asian	Sub	1008	T=0.443	G=0.557
1000Genomes	Europe	Sub	1006	T=0.574	G=0.426
1000Genomes	Global	Study-wide	5008	T=0.563	G=0.437
1000Genomes	South Asian	Sub	978	T=0.380	G=0.620
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.542	G=0.458
The Genome Aggregation Database	African	Sub	8682	T=0.775	G=0.225
The Genome Aggregation Database	American	Sub	832	T=0.470	G=0.530
The Genome Aggregation Database	East Asian	Sub	1538	T=0.412	G=0.588
The Genome Aggregation Database	Europe	Sub	18318	T=0.539	G=0.460
The Genome Aggregation Database	Global	Study-wide	29672	T=0.600	G=0.400
The Genome Aggregation Database	Other	Sub	302	T=0.570	G=0.430
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.651	G=0.348
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.528	G=0.472

PMID	Title	Author	Journal
23183491	Genome-wide association study identifies a potent locus associated with human opioid sensitivity.	Nishizawa D	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs1577822	0.000165	Opioid sensitivity	23183491

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs1577822