rs1580852

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0368 (11014/29892,GnomAD)
T=0485 (2428/5008,1000G)
T=0396 (1526/3854,ALSPAC)
T=0406 (1506/3708,TWINSUK)
chr8:16717603 (GRCh38.p7) (8p22)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.16717603C>T
GRCh37.p13 chr 8NC_000008.10:g.16575112C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.859T=0.141
1000GenomesAmericanSub694C=0.450T=0.550
1000GenomesEast AsianSub1008C=0.119T=0.881
1000GenomesEuropeSub1006C=0.587T=0.413
1000GenomesGlobalStudy-wide5008C=0.515T=0.485
1000GenomesSouth AsianSub978C=0.430T=0.570
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.604T=0.396
The Genome Aggregation DatabaseAfricanSub8696C=0.827T=0.173
The Genome Aggregation DatabaseAmericanSub834C=0.440T=0.560
The Genome Aggregation DatabaseEast AsianSub1618C=0.095T=0.905
The Genome Aggregation DatabaseEuropeSub18444C=0.594T=0.405
The Genome Aggregation DatabaseGlobalStudy-wide29892C=0.631T=0.368
The Genome Aggregation DatabaseOtherSub300C=0.710T=0.290
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.594T=0.406
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15808520.000471alcohol dependence20201924

eQTL of rs1580852 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1580852 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr81661285616613272E06737744
chr81654727516547419E070-27693
chr81654742616547751E070-27361