rs1580953

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0450 (13455/29894,GnomAD)
A=0406 (11823/29118,TOPMED)
A=0418 (2093/5008,1000G)
T==0484 (1865/3854,ALSPAC)
T==0484 (1795/3708,TWINSUK)
chr3:72105684 (GRCh38.p7) (3p13)
AD
GWASdb2
1   publication(s)
See rs on genome
167 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.72105684T>A
GRCh37.p13 chr 3NC_000003.11:g.72154835T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.736A=0.264
1000GenomesAmericanSub694T=0.480A=0.520
1000GenomesEast AsianSub1008T=0.578A=0.422
1000GenomesEuropeSub1006T=0.507A=0.493
1000GenomesGlobalStudy-wide5008T=0.582A=0.418
1000GenomesSouth AsianSub978T=0.530A=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.484A=0.516
The Genome Aggregation DatabaseAfricanSub8700T=0.707A=0.293
The Genome Aggregation DatabaseAmericanSub834T=0.460A=0.540
The Genome Aggregation DatabaseEast AsianSub1608T=0.574A=0.426
The Genome Aggregation DatabaseEuropeSub18452T=0.475A=0.524
The Genome Aggregation DatabaseGlobalStudy-wide29894T=0.549A=0.450
The Genome Aggregation DatabaseOtherSub300T=0.670A=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.594A=0.406
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.484A=0.516
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs15809538.42E-05alcohol consumption23743675

eQTL of rs1580953 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1580953 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr37212063872120693E067-34142
chr37212077572120860E067-33975
chr37218752272187692E06732687
chr37219319172193241E06738356
chr37219329772193460E06738462
chr37219363272193843E06738797
chr37219393772194320E06739102
chr37219433972194517E06739504
chr37219456072195128E06739725
chr37219513072195222E06740295
chr37219525172195446E06740416
chr37220139372201527E06746558
chr37220413372204428E06749298
chr37212665772127568E068-27267
chr37212774772127804E068-27031
chr37213943572139568E068-15267
chr37219319172193241E06838356
chr37219329772193460E06838462
chr37219363272193843E06838797
chr37219393772194320E06839102
chr37219433972194517E06839504
chr37219456072195128E06839725
chr37219513072195222E06840295
chr37220139372201527E06846558
chr37220313272203331E06848297
chr37220346472203508E06848629
chr37220413372204428E06849298
chr37211448472114671E069-40164
chr37211488672115113E069-39722
chr37214823972148300E069-6535
chr37214832372148434E069-6401
chr37214851172149086E069-5749
chr37215363372153878E069-957
chr37217817572178432E06923340
chr37219319172193241E06938356
chr37219329772193460E06938462
chr37219363272193843E06938797
chr37219393772194320E06939102
chr37219433972194517E06939504
chr37219456072195128E06939725
chr37219513072195222E06940295
chr37219525172195446E06940416
chr37219975372199826E06944918
chr37219985072199912E06945015
chr37219994672200991E06945111
chr37220139372201527E06946558
chr37220413372204428E06949298
chr37210691872107263E070-47572
chr37210760672108036E070-46799
chr37212665772127568E070-27267
chr37212774772127804E070-27031
chr37216036472160414E0705529
chr37216049972160729E0705664
chr37218752272187692E07032687
chr37219363272193843E07038797
chr37219393772194320E07039102
chr37219433972194517E07039504
chr37219456072195128E07039725
chr37219513072195222E07040295
chr37219525172195446E07040416
chr37219569772195747E07040862
chr37219595872196015E07041123
chr37220139372201527E07046558
chr37211488672115113E071-39722
chr37211527472115506E071-39329
chr37211556072115723E071-39112
chr37212774772127804E071-27031
chr37212786172127940E071-26895
chr37212798172128178E071-26657
chr37213943572139568E071-15267
chr37213978472140143E071-14692
chr37215119272151760E071-3075
chr37215195272152006E071-2829
chr37215213372152305E071-2530
chr37215363372153878E071-957
chr37218752272187692E07132687
chr37219048872191082E07135653
chr37219319172193241E07138356
chr37219329772193460E07138462
chr37219363272193843E07138797
chr37219393772194320E07139102
chr37219433972194517E07139504
chr37219456072195128E07139725
chr37219513072195222E07140295
chr37219975372199826E07144918
chr37219985072199912E07145015
chr37219994672200991E07145111
chr37220139372201527E07146558
chr37220313272203331E07148297
chr37220346472203508E07148629
chr37220413372204428E07149298
chr37211448472114671E072-40164
chr37211488672115113E072-39722
chr37211527472115506E072-39329
chr37213943572139568E072-15267
chr37218752272187692E07232687
chr37219048872191082E07235653
chr37219253372192755E07237698
chr37219319172193241E07238356
chr37219329772193460E07238462
chr37219363272193843E07238797
chr37219393772194320E07239102
chr37219433972194517E07239504
chr37219456072195128E07239725
chr37219513072195222E07240295
chr37219525172195446E07240416
chr37219994672200991E07245111
chr37220139372201527E07246558
chr37220413372204428E07249298
chr37219319172193241E07338356
chr37219329772193460E07338462
chr37219363272193843E07338797
chr37219393772194320E07339102
chr37219433972194517E07339504
chr37219456072195128E07339725
chr37219513072195222E07340295
chr37219525172195446E07340416
chr37220139372201527E07346558
chr37220413372204428E07349298
chr37211448472114671E074-40164
chr37211488672115113E074-39722
chr37211527472115506E074-39329
chr37211556072115723E074-39112
chr37213943572139568E074-15267
chr37213978472140143E074-14692
chr37215363372153878E074-957
chr37218415672184583E07429321
chr37219048872191082E07435653
chr37219127172191408E07436436
chr37219319172193241E07438356
chr37219329772193460E07438462
chr37219363272193843E07438797
chr37219393772194320E07439102
chr37219433972194517E07439504
chr37219456072195128E07439725
chr37219513072195222E07440295
chr37219525172195446E07440416
chr37219994672200991E07445111
chr37220139372201527E07446558
chr37220313272203331E07448297
chr37220346472203508E07448629
chr37220413372204428E07449298
chr37210691872107263E081-47572
chr37210760672108036E081-46799
chr37212855672128947E081-25888
chr37216036472160414E0815529
chr37216049972160729E0815664
chr37217817572178432E08123340
chr37217869272179216E08123857
chr37217936872179446E08124533
chr37218415672184583E08129321
chr37219433972194517E08139504
chr37219456072195128E08139725
chr37219513072195222E08140295
chr37219525172195446E08140416
chr37219569772195747E08140862
chr37220139372201527E08146558
chr37210691872107263E082-47572
chr37212665772127568E082-27267
chr37212774772127804E082-27031
chr37216036472160414E0825529
chr37216049972160729E0825664
chr37219393772194320E08239102
chr37219433972194517E08239504
chr37219456072195128E08239725
chr37219513072195222E08240295
chr37220139372201527E08246558