rs158810

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0210 (6302/29920,GnomAD)
C=0188 (5497/29118,TOPMED)
C=0287 (1435/5008,1000G)
C=0205 (789/3854,ALSPAC)
C=0224 (831/3708,TWINSUK)
chr5:74210286 (GRCh38.p7) (5q13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
70 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.74210286T>C
GRCh37.p13 chr 5NC_000005.9:g.73506111T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.877C=0.123
1000GenomesAmericanSub694T=0.650C=0.350
1000GenomesEast AsianSub1008T=0.544C=0.456
1000GenomesEuropeSub1006T=0.771C=0.229
1000GenomesGlobalStudy-wide5008T=0.713C=0.287
1000GenomesSouth AsianSub978T=0.650C=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.795C=0.205
The Genome Aggregation DatabaseAfricanSub8712T=0.873C=0.127
The Genome Aggregation DatabaseAmericanSub838T=0.650C=0.350
The Genome Aggregation DatabaseEast AsianSub1604T=0.541C=0.459
The Genome Aggregation DatabaseEuropeSub18464T=0.777C=0.222
The Genome Aggregation DatabaseGlobalStudy-wide29920T=0.789C=0.210
The Genome Aggregation DatabaseOtherSub302T=0.810C=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.811C=0.188
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.776C=0.224
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs1588100.00098alcohol dependence20201924

eQTL of rs158810 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs158810 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr57346323073463611E067-42500
chr57349682473497836E067-8275
chr57350137473501436E067-4675
chr57350150973501579E067-4532
chr57350170173503131E067-2980
chr57349682473497836E068-8275
chr57350170173503131E068-2980
chr57346323073463611E069-42500
chr57349640373496663E069-9448
chr57349682473497836E069-8275
chr57350170173503131E069-2980
chr57352235473522459E06916243
chr57352249773523593E06916386
chr57349640373496663E070-9448
chr57349682473497836E070-8275
chr57350137473501436E070-4675
chr57350150973501579E070-4532
chr57350170173503131E070-2980
chr57350314273503297E070-2814
chr57351001673510281E0703905
chr57351044073510521E0704329
chr57346037073461338E071-44773
chr57346323073463611E071-42500
chr57349640373496663E071-9448
chr57349682473497836E071-8275
chr57350170173503131E071-2980
chr57346323073463611E072-42500
chr57350170173503131E072-2980
chr57352249773523593E07216386
chr57349640373496663E073-9448
chr57350170173503131E073-2980
chr57350314273503297E073-2814
chr57352235473522459E07316243
chr57352249773523593E07316386
chr57350170173503131E074-2980
chr57345952373459708E081-46403
chr57345986373460311E081-45800
chr57346037073461338E081-44773
chr57347389173474420E081-31691
chr57350010873500347E081-5764
chr57350137473501436E081-4675
chr57350150973501579E081-4532
chr57350170173503131E081-2980
chr57350314273503297E081-2814
chr57350954173509628E0813430
chr57350985573509974E0813744
chr57351001673510281E0813905
chr57351859473518712E08112483
chr57351875773518890E08112646
chr57351906173519325E08112950
chr57352012773520546E08114016
chr57352058873520903E08114477
chr57352184873522047E08115737
chr57352210173522150E08115990
chr57352235473522459E08116243
chr57352249773523593E08116386
chr57355287373554352E08146762
chr57347389173474420E082-31691
chr57347465373474761E082-31350
chr57350010873500347E082-5764
chr57350137473501436E082-4675
chr57350150973501579E082-4532
chr57350170173503131E082-2980
chr57350314273503297E082-2814
chr57352012773520546E08214016
chr57352058873520903E08214477
chr57352184873522047E08215737
chr57352210173522150E08215990
chr57352235473522459E08216243
chr57352249773523593E08216386