rs1590255

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0110 (3320/29940,GnomAD)
G==0096 (2819/29102,TOPMED)
G==0133 (667/5008,1000G)
G==0086 (333/3854,ALSPAC)
G==0084 (311/3708,TWINSUK)
chr9:27233970 (GRCh38.p7) (9p21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.27233970G>T
GRCh37.p13 chr 9NC_000009.11:g.27233968G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.121T=0.879
1000GenomesAmericanSub694G=0.110T=0.890
1000GenomesEast AsianSub1008G=0.226T=0.774
1000GenomesEuropeSub1006G=0.089T=0.911
1000GenomesGlobalStudy-wide5008G=0.133T=0.867
1000GenomesSouth AsianSub978G=0.120T=0.880
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.086T=0.914
The Genome Aggregation DatabaseAfricanSub8712G=0.116T=0.884
The Genome Aggregation DatabaseAmericanSub836G=0.150T=0.850
The Genome Aggregation DatabaseEast AsianSub1610G=0.227T=0.773
The Genome Aggregation DatabaseEuropeSub18480G=0.097T=0.902
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.110T=0.889
The Genome Aggregation DatabaseOtherSub302G=0.070T=0.930
Trans-Omics for Precision MedicineGlobalStudy-wide29102G=0.096T=0.903
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.084T=0.916
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15902550.00033alcohol dependence(early age of onset)20201924
rs15902550.00085alcohol dependence20201924

eQTL of rs1590255 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1590255 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr92727592227276869E07041954
chr92728025627280363E07046288
chr92728037827280428E07046410
chr92728025627280363E08146288
chr92728037827280428E08146410
chr92727592227276869E08241954