rs1591068

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0207 (6103/29480,GnomAD)
A=0218 (6356/29118,TOPMED)
A=0264 (1320/5008,1000G)
A=0136 (525/3854,ALSPAC)
A=0133 (495/3708,TWINSUK)
chr9:91463255 (GRCh38.p7) (9q22.31)
AD
GWASdb2
1   publication(s)
See rs on genome
29 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.91463255G>A
GRCh37.p13 chr 9NC_000009.11:g.94225537G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.713A=0.287
1000GenomesAmericanSub694G=0.890A=0.110
1000GenomesEast AsianSub1008G=0.532A=0.468
1000GenomesEuropeSub1006G=0.866A=0.134
1000GenomesGlobalStudy-wide5008G=0.736A=0.264
1000GenomesSouth AsianSub978G=0.740A=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.864A=0.136
The Genome Aggregation DatabaseAfricanSub8672G=0.722A=0.278
The Genome Aggregation DatabaseAmericanSub824G=0.870A=0.130
The Genome Aggregation DatabaseEast AsianSub1610G=0.475A=0.525
The Genome Aggregation DatabaseEuropeSub18076G=0.852A=0.147
The Genome Aggregation DatabaseGlobalStudy-wide29480G=0.793A=0.207
The Genome Aggregation DatabaseOtherSub298G=0.800A=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.781A=0.218
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.867A=0.133
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15910680.0000821alcoholismpha002891
rs15910680.0000821alcohol dependence20201924

eQTL of rs1591068 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1591068 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr99424614994246455E06720612
chr99425117994251239E06725642
chr99425153694252118E06725999
chr99418138094182520E068-43017
chr99424509994246112E06919562
chr99424614994246455E06920612
chr99425117994251239E06925642
chr99425153694252118E06925999
chr99425214194252370E06926604
chr99423932594239480E07113788
chr99423951394239854E07113976
chr99425117994251239E07125642
chr99425153694252118E07125999
chr99425214194252370E07126604
chr99424509994246112E07219562
chr99424614994246455E07220612
chr99425153694252118E07225999
chr99425214194252370E07226604
chr99424509994246112E07319562
chr99423932594239480E07413788
chr99423951394239854E07413976
chr99425153694252118E07425999
chr99425214194252370E07426604
chr99418138094182520E081-43017
chr99419119394191687E081-33850
chr99419189994192117E081-33420
chr99419217894192218E081-33319
chr99418138094182520E082-43017
chr99419119394191687E082-33850









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr99418255894187945E067-37592
chr99418255894187945E068-37592
chr99418255894187945E069-37592
chr99418255894187945E070-37592
chr99418255894187945E071-37592
chr99418255894187945E072-37592
chr99418255894187945E073-37592
chr99418255894187945E074-37592
chr99418255894187945E081-37592
chr99418255894187945E082-37592