rs1605136

Homo sapiens
A>G / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
G=0465 (13881/29818,GnomAD)
G=0412 (12011/29118,TOPMED)
G=0407 (2036/5008,1000G)
G=0493 (1900/3854,ALSPAC)
G=0497 (1843/3708,TWINSUK)
chr2:139046571 (GRCh38.p7) (2q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.139046571A>G
GRCh38.p7 chr 2NC_000002.12:g.139046571A>T
GRCh37.p13 chr 2NC_000002.11:g.139804141A>G
GRCh37.p13 chr 2NC_000002.11:g.139804141A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.679G=0.321
1000GenomesAmericanSub694A=0.520G=0.480
1000GenomesEast AsianSub1008A=0.567G=0.433
1000GenomesEuropeSub1006A=0.548G=0.452
1000GenomesGlobalStudy-wide5008A=0.593G=0.407
1000GenomesSouth AsianSub978A=0.610G=0.390
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.507G=0.493
The Genome Aggregation DatabaseAfricanSub8700A=0.664G=0.336
The Genome Aggregation DatabaseAmericanSub832A=0.540G=0.46,
The Genome Aggregation DatabaseEast AsianSub1566A=0.611G=0.389
The Genome Aggregation DatabaseEuropeSub18420A=0.466G=0.533
The Genome Aggregation DatabaseGlobalStudy-wide29818A=0.534G=0.465
The Genome Aggregation DatabaseOtherSub300A=0.530G=0.47,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.587G=0.412
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.503G=0.497
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs16051367.51E-05alcohol dependence21703634

eQTL of rs1605136 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1605136 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr26314058563140732E070-27213
chr26313011663130229E072-37716
chr26319426763194433E08126322