SNP Detail Info-rs160816

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0438 (13102/29910,GnomAD)
A=0466 (13592/29118,TOPMED)
A=0483 (2417/5008,1000G)
A=0368 (1417/3854,ALSPAC)
A=0365 (1352/3708,TWINSUK)

Position: chr13:93099704 (GRCh38.p7) (13q31.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 13	NC_000013.11:g.93099704G>A
GRCh37.p13 chr 13	NC_000013.10:g.93751957G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.400	A=0.600
1000Genomes	American	Sub	694	G=0.420	A=0.580
1000Genomes	East Asian	Sub	1008	G=0.513	A=0.487
1000Genomes	Europe	Sub	1006	G=0.645	A=0.355
1000Genomes	Global	Study-wide	5008	G=0.517	A=0.483
1000Genomes	South Asian	Sub	978	G=0.620	A=0.380
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.632	A=0.368
The Genome Aggregation Database	African	Sub	8698	G=0.424	A=0.576
The Genome Aggregation Database	American	Sub	838	G=0.410	A=0.590
The Genome Aggregation Database	East Asian	Sub	1614	G=0.532	A=0.468
The Genome Aggregation Database	Europe	Sub	18460	G=0.636	A=0.363
The Genome Aggregation Database	Global	Study-wide	29910	G=0.562	A=0.438
The Genome Aggregation Database	Other	Sub	300	G=0.590	A=0.410
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.533	A=0.466
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.635	A=0.365

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs160816	9.2E-05	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr13	93727717	93727913	E070	-24044
chr13	93727955	93728187	E070	-23770
chr13	93728818	93728868	E070	-23089

rs160816