rs1622626

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0351 (10488/29876,GnomAD)
C=0386 (11257/29118,TOPMED)
C=0403 (2016/5008,1000G)
C=0204 (785/3854,ALSPAC)
C=0207 (768/3708,TWINSUK)
chr10:58172751 (GRCh38.p7) (10q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.58172751A>C
GRCh37.p13 chr 10NC_000010.10:g.59932512A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.315C=0.685
1000GenomesAmericanSub694A=0.750C=0.250
1000GenomesEast AsianSub1008A=0.559C=0.441
1000GenomesEuropeSub1006A=0.787C=0.213
1000GenomesGlobalStudy-wide5008A=0.597C=0.403
1000GenomesSouth AsianSub978A=0.720C=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.796C=0.204
The Genome Aggregation DatabaseAfricanSub8704A=0.398C=0.602
The Genome Aggregation DatabaseAmericanSub836A=0.770C=0.230
The Genome Aggregation DatabaseEast AsianSub1598A=0.535C=0.465
The Genome Aggregation DatabaseEuropeSub18436A=0.769C=0.230
The Genome Aggregation DatabaseGlobalStudy-wide29876A=0.648C=0.351
The Genome Aggregation DatabaseOtherSub302A=0.800C=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.613C=0.386
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.793C=0.207
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs16226260.000736nicotine dependence17158188

eQTL of rs1622626 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1622626 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr105989384659893918E068-38594
chr105991293559913007E069-19505
chr105989211959892204E070-40308
chr105989384659893918E070-38594
chr105989410459894158E070-38354
chr105989711059897160E070-35352
chr105989813359898262E070-34250
chr105989837959898519E070-33993
chr105993848059939107E0705968
chr105993913559939321E0706623
chr105993964559939782E0707133
chr105989711059897160E071-35352
chr105989711059897160E074-35352
chr105989813359898262E074-34250