rs1623319

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0283 (8491/29938,GnomAD)
A=0270 (7884/29118,TOPMED)
A=0337 (1686/5008,1000G)
A=0269 (1035/3854,ALSPAC)
A=0263 (977/3708,TWINSUK)
chr12:75876976 (GRCh38.p7) (12q21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.75876976G>A
GRCh37.p13 chr 12NC_000012.11:g.76270756G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.679A=0.321
1000GenomesAmericanSub694G=0.860A=0.140
1000GenomesEast AsianSub1008G=0.484A=0.516
1000GenomesEuropeSub1006G=0.756A=0.244
1000GenomesGlobalStudy-wide5008G=0.663A=0.337
1000GenomesSouth AsianSub978G=0.590A=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.731A=0.269
The Genome Aggregation DatabaseAfricanSub8716G=0.687A=0.313
The Genome Aggregation DatabaseAmericanSub836G=0.850A=0.150
The Genome Aggregation DatabaseEast AsianSub1616G=0.475A=0.525
The Genome Aggregation DatabaseEuropeSub18468G=0.743A=0.256
The Genome Aggregation DatabaseGlobalStudy-wide29938G=0.716A=0.283
The Genome Aggregation DatabaseOtherSub302G=0.820A=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.729A=0.270
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.737A=0.263
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs16233199.3E-05alcoholism (heaviness of drinking)21529783

eQTL of rs1623319 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1623319 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr127623545676235663E067-35093
chr127624188176243190E067-27566
chr127624324076243290E067-27466
chr127628347476283662E06712718
chr127628367376283794E06712917
chr127629413776294430E06723381
chr127629446676294749E06723710
chr127623545676235663E068-35093
chr127623585476236222E068-34534
chr127624188176243190E068-27566
chr127627051476272644E0680
chr127627708076277130E0686324
chr127628380576283892E06813049
chr127628402276284243E06813266
chr127630231376304443E06831557
chr127623510176235190E069-35566
chr127623528476235334E069-35422
chr127623623676236333E069-34423
chr127624188176243190E069-27566
chr127628367376283794E06912917
chr127628380576283892E06913049
chr127623136076232160E070-38596
chr127623457276234747E070-36009
chr127623510176235190E070-35566
chr127623528476235334E070-35422
chr127623545676235663E070-35093
chr127623585476236222E070-34534
chr127623623676236333E070-34423
chr127623673176236781E070-33975
chr127623696376237025E070-33731
chr127623703076237239E070-33517
chr127623797576239413E070-31343
chr127623951576239568E070-31188
chr127623987776239937E070-30819
chr127624009176240145E070-30611
chr127624027876240359E070-30397
chr127624163176241771E070-28985
chr127624188176243190E070-27566
chr127624324076243290E070-27466
chr127624383076243922E070-26834
chr127624429276244419E070-26337
chr127624445476245069E070-25687
chr127624507876245195E070-25561
chr127624521876245558E070-25198
chr127624657076247077E070-23679
chr127624728276247852E070-22904
chr127626233476262668E070-8088
chr127627021176270274E070-482
chr127627051476272644E0700
chr127627661076276688E0705854
chr127627708076277130E0706324
chr127627718576277298E0706429
chr127628347476283662E07012718
chr127628367376283794E07012917
chr127628380576283892E07013049
chr127628402276284243E07013266
chr127628457576284672E07013819
chr127629391376294032E07023157
chr127629413776294430E07023381
chr127629446676294749E07023710
chr127629481576294894E07024059
chr127629494476295064E07024188
chr127623545676235663E071-35093
chr127623585476236222E071-34534
chr127623623676236333E071-34423
chr127624188176243190E071-27566
chr127624324076243290E071-27466
chr127628347476283662E07112718
chr127628367376283794E07112917
chr127628380576283892E07113049
chr127628402276284243E07113266
chr127628457576284672E07113819
chr127628469776284918E07113941
chr127630231376304443E07131557
chr127623545676235663E072-35093
chr127624188176243190E072-27566
chr127628186776281970E07211111
chr127628367376283794E07212917
chr127623545676235663E073-35093
chr127623585476236222E073-34534
chr127624188176243190E073-27566
chr127623545676235663E074-35093
chr127623585476236222E074-34534
chr127623623676236333E074-34423
chr127624163176241771E074-28985
chr127624188176243190E074-27566
chr127625878476258861E074-11895
chr127628347476283662E07412718
chr127628367376283794E07412917
chr127628380576283892E07413049
chr127629413776294430E07423381
chr127629446676294749E07423710
chr127630231376304443E07431557
chr127623075376231283E081-39473
chr127623136076232160E081-38596
chr127623545676235663E081-35093
chr127624188176243190E081-27566
chr127627051476272644E0810
chr127627267876272790E0811922
chr127627579076276028E0815034
chr127627615076276409E0815394
chr127627661076276688E0815854
chr127628226876282359E08111512
chr127628280876283384E08112052
chr127628347476283662E08112718
chr127628380576283892E08113049
chr127628402276284243E08113266
chr127623422876234327E082-36429
chr127623443776234511E082-36245
chr127623457276234747E082-36009
chr127623510176235190E082-35566
chr127623528476235334E082-35422
chr127623545676235663E082-35093
chr127623951576239568E082-31188
chr127624188176243190E082-27566
chr127627051476272644E0820
chr127628347476283662E08212718
chr127628367376283794E08212917
chr127629413776294430E08223381
chr127629446676294749E08223710