rs1637995

Homo sapiens
A>G
ARID3A : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0047 (1418/29840,GnomAD)
A==0061 (303/5008,1000G)
A==0023 (90/3854,ALSPAC)
A==0023 (87/3708,TWINSUK)
chr19:960445 (GRCh38.p7) (19p13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
86 Enhancers around
35 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.960445A>G
GRCh37.p13 chr 19NC_000019.9:g.960445A>G

Gene: ARID3A, AT-rich interaction domain 3A(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ARID3A transcriptNM_005224.2:c.N/AIntron Variant
ARID3A transcript variant X2XM_005259513.4:c.N/AIntron Variant
ARID3A transcript variant X3XM_005259514.4:c.N/AIntron Variant
ARID3A transcript variant X1XM_017026445.1:c.N/AIntron Variant
ARID3A transcript variant X5XM_017026446.1:c.N/AIntron Variant
ARID3A transcript variant X5XM_017026447.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.136G=0.864
1000GenomesAmericanSub694A=0.090G=0.910
1000GenomesEast AsianSub1008A=0.000G=1.000
1000GenomesEuropeSub1006A=0.024G=0.976
1000GenomesGlobalStudy-wide5008A=0.061G=0.939
1000GenomesSouth AsianSub978A=0.040G=0.960
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.023G=0.977
The Genome Aggregation DatabaseAfricanSub8684A=0.115G=0.885
The Genome Aggregation DatabaseAmericanSub838A=0.130G=0.870
The Genome Aggregation DatabaseEast AsianSub1612A=0.001G=0.999
The Genome Aggregation DatabaseEuropeSub18404A=0.016G=0.983
The Genome Aggregation DatabaseGlobalStudy-wide29840A=0.047G=0.952
The Genome Aggregation DatabaseOtherSub302A=0.010G=0.990
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.023G=0.977
PMID Title Author Journal
21956439Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.Zuo LNeuropsychopharmacology

P-Value

SNP ID p-value Traits Study
rs16379959E-06alcohol dependence21956439

eQTL of rs1637995 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1637995 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr19934363934478E067-25967
chr19934480935588E067-24857
chr19940207940264E067-20181
chr19950706950795E067-9650
chr19983359983479E06722914
chr19983553983756E06723108
chr19921255922241E068-38204
chr19934363934478E068-25967
chr19934480935588E068-24857
chr19941664941993E068-18452
chr19983359983479E06822914
chr19983553983756E06823108
chr19924549924589E069-35856
chr19934077934218E069-26227
chr19934228934292E069-26153
chr19934363934478E069-25967
chr19934480935588E069-24857
chr19941664941993E069-18452
chr19983359983479E06922914
chr19983553983756E06923108
chr19995473995566E06935028
chr19934228934292E070-26153
chr19934363934478E070-25967
chr19934480935588E070-24857
chr19940207940264E070-20181
chr19941664941993E070-18452
chr19942242942572E070-17873
chr19942585942669E070-17776
chr19944845945548E070-14897
chr19955812957516E070-2929
chr19983359983479E07022914
chr19983553983756E07023108
chr19985442985779E07024997
chr19985854986068E07025409
chr19932501933991E071-26454
chr19934077934218E071-26227
chr19934228934292E071-26153
chr19934363934478E071-25967
chr19934480935588E071-24857
chr19936083936133E071-24312
chr19936178936228E071-24217
chr19940207940264E071-20181
chr19941664941993E071-18452
chr19983359983479E07122914
chr19983553983756E07123108
chr19934363934478E072-25967
chr19934480935588E072-24857
chr19941664941993E072-18452
chr19983359983479E07222914
chr19983553983756E07223108
chr19921255922241E073-38204
chr19924549924589E073-35856
chr19932501933991E073-26454
chr19934077934218E073-26227
chr19934228934292E073-26153
chr19934363934478E073-25967
chr19934480935588E073-24857
chr19921255922241E074-38204
chr19934077934218E074-26227
chr19934228934292E074-26153
chr19934363934478E074-25967
chr19934480935588E074-24857
chr19941664941993E074-18452
chr19983359983479E07422914
chr19983553983756E07423108
chr19921255922241E081-38204
chr19934077934218E081-26227
chr19934228934292E081-26153
chr19934363934478E081-25967
chr19934480935588E081-24857
chr19940207940264E081-20181
chr19941664941993E081-18452
chr19983359983479E08122914
chr19983553983756E08123108
chr19985276985326E08124831
chr19985442985779E08124997
chr19924549924589E082-35856
chr19934480935588E082-24857
chr19940207940264E082-20181
chr19941664941993E082-18452
chr19944845945548E082-14897
chr19985276985326E08224831
chr19985442985779E08224997
chr19985854986068E08225409
chr19986132986303E08225687
chr19986710986821E08226265










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr19912269913999E067-46446
chr19924602929275E067-31170
chr19983831985184E06723386
chr19912269913999E068-46446
chr19918390920613E068-39832
chr19920645921155E068-39290
chr19924602929275E068-31170
chr19983831985184E06823386
chr19912269913999E069-46446
chr19920645921155E069-39290
chr19924602929275E069-31170
chr19983831985184E06923386
chr19911514912264E070-48181
chr19912269913999E070-46446
chr19918390920613E070-39832
chr19924602929275E070-31170
chr19983831985184E07023386
chr19911514912264E071-48181
chr19912269913999E071-46446
chr19924602929275E071-31170
chr19983831985184E07123386
chr19912269913999E072-46446
chr19924602929275E072-31170
chr19983831985184E07223386
chr19912269913999E073-46446
chr19924602929275E073-31170
chr19983831985184E07323386
chr19912269913999E074-46446
chr19983831985184E07423386
chr19911514912264E082-48181
chr19912269913999E082-46446
chr19918390920613E082-39832
chr19924602929275E082-31170
chr19983831985184E08223386
chr1910001181000408E08239673