rs1660895

Homo sapiens
A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0484 (14460/29872,GnomAD)
A==0457 (13313/29118,TOPMED)
T=0474 (2372/5008,1000G)
A==0477 (1840/3854,ALSPAC)
A==0493 (1827/3708,TWINSUK)
chr2:129236759 (GRCh38.p7) (2q21.1)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129236759A>T
GRCh37.p13 chr 2NC_000002.11:g.129994332A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.380T=0.620
1000GenomesAmericanSub694A=0.540T=0.460
1000GenomesEast AsianSub1008A=0.745T=0.255
1000GenomesEuropeSub1006A=0.464T=0.536
1000GenomesGlobalStudy-wide5008A=0.526T=0.474
1000GenomesSouth AsianSub978A=0.560T=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.477T=0.523
The Genome Aggregation DatabaseAfricanSub8690A=0.421T=0.579
The Genome Aggregation DatabaseAmericanSub834A=0.550T=0.450
The Genome Aggregation DatabaseEast AsianSub1616A=0.804T=0.196
The Genome Aggregation DatabaseEuropeSub18430A=0.483T=0.516
The Genome Aggregation DatabaseGlobalStudy-wide29872A=0.484T=0.515
The Genome Aggregation DatabaseOtherSub302A=0.440T=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.457T=0.542
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.493T=0.507
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs16608957E-07alcohol dependence (age at onset)24962325

eQTL of rs1660895 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1660895 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-3310
chr2129991443129991904E070-2428
chr2129990903129991022E081-3310
chr2129991443129991904E081-2428
chr2129996773129997036E0812441
chr2130010223130010353E08115891
chr2130010398130011293E08116066
chr2130038915130039052E08144583
chr2130039472130039687E08145140
chr2130039843130039996E08145511
chr2129996773129997036E0822441
chr2130010223130010353E08215891
chr2130038591130038845E08244259
chr2130038915130039052E08244583
chr2130039472130039687E08245140
chr2130039843130039996E08245511