SNP Detail Info-rs166093

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

ARL15 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0270 (8091/29882,GnomAD)
G==0269 (7840/29118,TOPMED)
G==0350 (1754/5008,1000G)
G==0262 (1010/3854,ALSPAC)
G==0254 (942/3708,TWINSUK)

Position: chr5:54245095 (GRCh38.p7) (5q11.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 14 Enhancers around

Promoter: 1 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.54245095G>A
GRCh37.p13 chr 5	NC_000005.9:g.53540925G>A

Molecule type	Change	Amino acid[Codon]	SO Term
ARL15 transcript	NM_019087.2:c.	N/A	Intron Variant
ARL15 transcript variant X1	XM_011543498.2:c.	N/A	Intron Variant
ARL15 transcript variant X2	XM_011543499.2:c.	N/A	Intron Variant
ARL15 transcript variant X3	XM_011543500.2:c.	N/A	Intron Variant
ARL15 transcript variant X4	XM_017009598.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.234	A=0.766
1000Genomes	American	Sub	694	G=0.470	A=0.530
1000Genomes	East Asian	Sub	1008	G=0.554	A=0.446
1000Genomes	Europe	Sub	1006	G=0.250	A=0.750
1000Genomes	Global	Study-wide	5008	G=0.350	A=0.650
1000Genomes	South Asian	Sub	978	G=0.320	A=0.680
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.262	A=0.738
The Genome Aggregation Database	African	Sub	8710	G=0.238	A=0.762
The Genome Aggregation Database	American	Sub	830	G=0.480	A=0.520
The Genome Aggregation Database	East Asian	Sub	1612	G=0.585	A=0.415
The Genome Aggregation Database	Europe	Sub	18428	G=0.250	A=0.749
The Genome Aggregation Database	Global	Study-wide	29882	G=0.270	A=0.729
The Genome Aggregation Database	Other	Sub	302	G=0.210	A=0.790
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.269	A=0.730
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.254	A=0.746

PMID	Title	Author	Journal
24962325	Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.	Kapoor M	Drug Alcohol Depend

SNP ID	p-value	Traits	Study
rs166093	2.9E-06	alcohol dependence (age at onset)	24962325

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	53524921	53525456	E068	-15469
chr5	53573941	53574185	E069	33016
chr5	53574222	53574433	E069	33297
chr5	53510666	53510874	E070	-30051
chr5	53511150	53511650	E070	-29275
chr5	53513271	53513323	E070	-27602
chr5	53573941	53574185	E072	33016
chr5	53574222	53574433	E072	33297
chr5	53574445	53574505	E072	33520
chr5	53574222	53574433	E074	33297
chr5	53574445	53574505	E074	33520
chr5	53510666	53510874	E081	-30051
chr5	53511150	53511650	E081	-29275
chr5	53511150	53511650	E082	-29275

rs166093