rs166093

Homo sapiens
G>A
ARL15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0270 (8091/29882,GnomAD)
G==0269 (7840/29118,TOPMED)
G==0350 (1754/5008,1000G)
G==0262 (1010/3854,ALSPAC)
G==0254 (942/3708,TWINSUK)
chr5:54245095 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.54245095G>A
GRCh37.p13 chr 5NC_000005.9:g.53540925G>A

Gene: ARL15, ADP ribosylation factor like GTPase 15(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL15 transcriptNM_019087.2:c.N/AIntron Variant
ARL15 transcript variant X1XM_011543498.2:c.N/AIntron Variant
ARL15 transcript variant X2XM_011543499.2:c.N/AIntron Variant
ARL15 transcript variant X3XM_011543500.2:c.N/AIntron Variant
ARL15 transcript variant X4XM_017009598.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.234A=0.766
1000GenomesAmericanSub694G=0.470A=0.530
1000GenomesEast AsianSub1008G=0.554A=0.446
1000GenomesEuropeSub1006G=0.250A=0.750
1000GenomesGlobalStudy-wide5008G=0.350A=0.650
1000GenomesSouth AsianSub978G=0.320A=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.262A=0.738
The Genome Aggregation DatabaseAfricanSub8710G=0.238A=0.762
The Genome Aggregation DatabaseAmericanSub830G=0.480A=0.520
The Genome Aggregation DatabaseEast AsianSub1612G=0.585A=0.415
The Genome Aggregation DatabaseEuropeSub18428G=0.250A=0.749
The Genome Aggregation DatabaseGlobalStudy-wide29882G=0.270A=0.729
The Genome Aggregation DatabaseOtherSub302G=0.210A=0.790
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.269A=0.730
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.254A=0.746
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs1660932.9E-06alcohol dependence (age at onset)24962325

eQTL of rs166093 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs166093 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55352492153525456E068-15469
chr55357394153574185E06933016
chr55357422253574433E06933297
chr55351066653510874E070-30051
chr55351115053511650E070-29275
chr55351327153513323E070-27602
chr55357394153574185E07233016
chr55357422253574433E07233297
chr55357444553574505E07233520
chr55357422253574433E07433297
chr55357444553574505E07433520
chr55351066653510874E081-30051
chr55351115053511650E081-29275
chr55351115053511650E082-29275







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55355060653550896E0719681