rs1667284

Homo sapiens
A>G
B4GALT6 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0420 (12587/29910,GnomAD)
A==0352 (10249/29118,TOPMED)
A==0416 (2082/5008,1000G)
G=0482 (1858/3854,ALSPAC)
G=0474 (1759/3708,TWINSUK)
chr18:31646245 (GRCh38.p7) (18q12.1)
AD
GWASCatalog
1   publication(s)
See rs on genome
58 Enhancers around
22 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.31646245A>G
GRCh37.p13 chr 18NC_000018.9:g.29226208A>G

Gene: B4GALT6, beta-1,4-galactosyltransferase 6(minus strand)

Molecule type Change Amino acid[Codon] SO Term
B4GALT6 transcript variant 1NM_004775.3:c.N/AIntron Variant
B4GALT6 transcript variant X1XM_005258387.4:c.N/AIntron Variant
B4GALT6 transcript variant X2XM_006722578.3:c.N/AIntron Variant
B4GALT6 transcript variant X4XM_006722579.3:c.N/AIntron Variant
B4GALT6 transcript variant X3XM_017026088.1:c.N/AIntron Variant
B4GALT6 transcript variant X5XM_017026089.1:c.N/AIntron Variant
B4GALT6 transcript variant X5XM_017026090.1:c.N/AIntron Variant
B4GALT6 transcript variant X6XM_017026091.1:c.N/AIntron Variant
B4GALT6 transcript variant X8XM_017026092.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.092G=0.908
1000GenomesAmericanSub694A=0.470G=0.530
1000GenomesEast AsianSub1008A=0.576G=0.424
1000GenomesEuropeSub1006A=0.497G=0.503
1000GenomesGlobalStudy-wide5008A=0.416G=0.584
1000GenomesSouth AsianSub978A=0.570G=0.430
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.518G=0.482
The Genome Aggregation DatabaseAfricanSub8722A=0.145G=0.855
The Genome Aggregation DatabaseAmericanSub828A=0.530G=0.470
The Genome Aggregation DatabaseEast AsianSub1614A=0.558G=0.442
The Genome Aggregation DatabaseEuropeSub18444A=0.533G=0.466
The Genome Aggregation DatabaseGlobalStudy-wide29910A=0.420G=0.579
The Genome Aggregation DatabaseOtherSub302A=0.470G=0.530
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.352G=0.648
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.526G=0.474
PMID Title Author Journal
29082582Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.Almli LMAddict Biol

P-Value

SNP ID p-value Traits Study
rs16672844E-06alcohol dependence29082582

eQTL of rs1667284 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1667284 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr182922476029224913E068-1295
chr182922494229225009E068-1199
chr182922507729225117E068-1091
chr182922551429225924E068-284
chr182922596529226242E0680
chr182922629629226598E06888
chr182922665729226993E068449
chr182922805029228098E0681842
chr182922838429228511E0682176
chr182922890629229343E0682698
chr182922838429228511E0692176
chr182922890629229343E0692698
chr182919059729191184E070-35024
chr182919123629191332E070-34876
chr182919135729191427E070-34781
chr182919146729191572E070-34636
chr182919165029191720E070-34488
chr182919178129191863E070-34345
chr182922494229225009E070-1199
chr182922507729225117E070-1091
chr182922551429225924E070-284
chr182922596529226242E0700
chr182922629629226598E07088
chr182922665729226993E070449
chr182922701329227525E070805
chr182922770029227808E0701492
chr182922791329227994E0701705
chr182922805029228098E0701842
chr182922838429228511E0702176
chr182922665729226993E071449
chr182922701329227525E071805
chr182922770029227808E0711492
chr182922791329227994E0711705
chr182922805029228098E0711842
chr182922838429228511E0712176
chr182922890629229343E0712698
chr182922838429228511E0732176
chr182922890629229343E0732698
chr182922805029228098E0741842
chr182922838429228511E0742176
chr182922890629229343E0742698
chr182925767729257932E07431469
chr182925794529258007E07431737
chr182925801129258134E07431803
chr182925814629258257E07431938
chr182918995329190167E081-36041
chr182919028429190492E081-35716
chr182919059729191184E081-35024
chr182918972929189798E082-36410
chr182918995329190167E082-36041
chr182919028429190492E082-35716
chr182919059729191184E082-35024
chr182919123629191332E082-34876
chr182919135729191427E082-34781
chr182919146729191572E082-34636
chr182919165029191720E082-34488
chr182919178129191863E082-34345
chr182923542029235575E0829212








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr182926319029263270E06736982
chr182926346029263511E06737252
chr182926365029266295E06737442
chr182926319029263270E06836982
chr182926346029263511E06837252
chr182926365029266295E06837442
chr182926319029263270E06936982
chr182926346029263511E06937252
chr182926365029266295E06937442
chr182926319029263270E07036982
chr182926346029263511E07037252
chr182926365029266295E07037442
chr182926365029266295E07137442
chr182926365029266295E07237442
chr182926319029263270E07336982
chr182926346029263511E07337252
chr182926365029266295E07337442
chr182926365029266295E07437442
chr182926365029266295E08137442
chr182926319029263270E08236982
chr182926346029263511E08237252
chr182926365029266295E08237442