rs1670160

Homo sapiens
C>T
LOC105378338 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0205 (6149/29888,GnomAD)
T=0258 (7534/29118,TOPMED)
T=0209 (1048/5008,1000G)
T=0134 (516/3854,ALSPAC)
T=0128 (475/3708,TWINSUK)
chr10:65785302 (GRCh38.p7) (10q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.65785302C>T
GRCh37.p13 chr 10NC_000010.10:g.67545060C>T

Gene: LOC105378338, uncharacterized LOC105378338(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105378338 transcriptXR_001747477.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.517T=0.483
1000GenomesAmericanSub694C=0.880T=0.120
1000GenomesEast AsianSub1008C=0.943T=0.057
1000GenomesEuropeSub1006C=0.873T=0.127
1000GenomesGlobalStudy-wide5008C=0.791T=0.209
1000GenomesSouth AsianSub978C=0.850T=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.866T=0.134
The Genome Aggregation DatabaseAfricanSub8670C=0.586T=0.414
The Genome Aggregation DatabaseAmericanSub836C=0.880T=0.120
The Genome Aggregation DatabaseEast AsianSub1618C=0.944T=0.056
The Genome Aggregation DatabaseEuropeSub18462C=0.874T=0.125
The Genome Aggregation DatabaseGlobalStudy-wide29888C=0.794T=0.205
The Genome Aggregation DatabaseOtherSub302C=0.810T=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.741T=0.258
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.872T=0.128
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs16701600.000935alcohol dependence20201924

eQTL of rs1670160 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1670160 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr106754792767548753E0812867
chr106756489267565021E08119832
chr106756507667565147E08120016
chr106756523767565906E08120177
chr106756594767566114E08120887
chr106756616167566299E08121101
chr106756650967566613E08121449

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr106752454367525147E068-19913
chr106752454367525147E072-19913