rs1674512

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0392 (11748/29924,GnomAD)
G==0422 (12306/29118,TOPMED)
G==0412 (2062/5008,1000G)
G==0364 (1401/3854,ALSPAC)
G==0363 (1345/3708,TWINSUK)
chr5:50268794 (GRCh38.p7) (5q11.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.50268794G>A
GRCh37.p13 chr 5NC_000005.9:g.49564628G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.509A=0.491
1000GenomesAmericanSub694G=0.330A=0.670
1000GenomesEast AsianSub1008G=0.474A=0.526
1000GenomesEuropeSub1006G=0.331A=0.669
1000GenomesGlobalStudy-wide5008G=0.412A=0.588
1000GenomesSouth AsianSub978G=0.360A=0.640
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.364A=0.636
The Genome Aggregation DatabaseAfricanSub8704G=0.522A=0.478
The Genome Aggregation DatabaseAmericanSub838G=0.340A=0.660
The Genome Aggregation DatabaseEast AsianSub1612G=0.515A=0.485
The Genome Aggregation DatabaseEuropeSub18468G=0.324A=0.675
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.392A=0.607
The Genome Aggregation DatabaseOtherSub302G=0.320A=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.422A=0.577
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.363A=0.637
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs16745120.0000915alcoholismpha002891
rs16745120.0000915alcohol dependence20201924

eQTL of rs1674512 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1674512 in Fetal Brain

Probe ID Position Gene beta p-value
cg15950743chr5:49708521EMB-0.08887719117714872.2598e-35

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.