rs1681300

Homo sapiens
G>A
LOC107986767 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0351 (10529/29952,GnomAD)
A=0305 (8902/29118,TOPMED)
A=0296 (1481/5008,1000G)
A=0415 (1600/3854,ALSPAC)
A=0418 (1551/3708,TWINSUK)
chr7:10950685 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
50 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.10950685G>A
GRCh37.p13 chr 7NC_000007.13:g.10990312G>A

Gene: LOC107986767, uncharacterized LOC107986767(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107986767 transcriptXR_001745091.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.869A=0.131
1000GenomesAmericanSub694G=0.630A=0.370
1000GenomesEast AsianSub1008G=0.851A=0.149
1000GenomesEuropeSub1006G=0.559A=0.441
1000GenomesGlobalStudy-wide5008G=0.704A=0.296
1000GenomesSouth AsianSub978G=0.530A=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.585A=0.415
The Genome Aggregation DatabaseAfricanSub8716G=0.821A=0.179
The Genome Aggregation DatabaseAmericanSub838G=0.620A=0.380
The Genome Aggregation DatabaseEast AsianSub1618G=0.873A=0.127
The Genome Aggregation DatabaseEuropeSub18480G=0.550A=0.449
The Genome Aggregation DatabaseGlobalStudy-wide29952G=0.648A=0.351
The Genome Aggregation DatabaseOtherSub300G=0.540A=0.460
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.694A=0.305
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.582A=0.418
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs16813000.000737alcohol dependence21314694

eQTL of rs1681300 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1681300 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr71097461710974817E067-15495
chr71097484110974892E067-15420
chr71097490610975041E067-15271
chr71097509310975207E067-15105
chr71097524510975363E067-14949
chr71097461710974817E068-15495
chr71097484110974892E068-15420
chr71097490610975041E068-15271
chr71097509310975207E068-15105
chr71097524510975363E068-14949
chr71097544610975496E068-14816
chr71097552210975572E068-14740
chr71097668810976728E068-13584
chr71097461710974817E069-15495
chr71097484110974892E069-15420
chr71097490610975041E069-15271
chr71097509310975207E069-15105
chr71097524510975363E069-14949
chr71097544610975496E069-14816
chr71097552210975572E069-14740
chr71101551011016022E06925198
chr71097814910978189E070-12123
chr71101551011016022E07025198
chr71097461710974817E071-15495
chr71097484110974892E071-15420
chr71097490610975041E071-15271
chr71097509310975207E071-15105
chr71097524510975363E071-14949
chr71097544610975496E071-14816
chr71097552210975572E071-14740
chr71097579810975876E071-14436
chr71097588710976017E071-14295
chr71097814910978189E071-12123
chr71097461710974817E072-15495
chr71097484110974892E072-15420
chr71097490610975041E072-15271
chr71097544610975496E072-14816
chr71097552210975572E072-14740
chr71097490610975041E074-15271
chr71097509310975207E074-15105
chr71097524510975363E074-14949
chr71097544610975496E074-14816
chr71097552210975572E074-14740
chr71097579810975876E074-14436
chr71097588710976017E074-14295
chr71103938211039432E07449070
chr71101510511015151E08124793
chr71101551011016022E08125198
chr71101510511015151E08224793
chr71101551011016022E08225198









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr71097852110978765E067-11547
chr71097884110981470E067-8842
chr71101226011014703E06721948
chr71097852110978765E068-11547
chr71097884110981470E068-8842
chr71101226011014703E06821948
chr71097852110978765E069-11547
chr71097884110981470E069-8842
chr71101226011014703E06921948
chr71097852110978765E070-11547
chr71097884110981470E070-8842
chr71101226011014703E07021948
chr71097852110978765E071-11547
chr71097884110981470E071-8842
chr71101226011014703E07121948
chr71097852110978765E072-11547
chr71097884110981470E072-8842
chr71101226011014703E07221948
chr71097852110978765E073-11547
chr71097884110981470E073-8842
chr71101226011014703E07321948
chr71097852110978765E074-11547
chr71097884110981470E074-8842
chr71101226011014703E07421948
chr71097852110978765E081-11547
chr71101226011014703E08121948
chr71097852110978765E082-11547
chr71097884110981470E082-8842
chr71101226011014703E08221948