SNP Detail Info-rs16834223

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0070 (2120/29964,GnomAD)
G=0070 (2040/29118,TOPMED)
G=0094 (470/5008,1000G)
G=0065 (250/3854,ALSPAC)
G=0073 (270/3708,TWINSUK)

Position: chr2:136436866 (GRCh38.p7) (2q22.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 13 Enhancers around

Promoter: 17 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.136436866A>G
GRCh37.p13 chr 2	NC_000002.11:g.137194436A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.950	G=0.050
1000Genomes	American	Sub	694	A=0.930	G=0.070
1000Genomes	East Asian	Sub	1008	A=0.893	G=0.107
1000Genomes	Europe	Sub	1006	A=0.886	G=0.114
1000Genomes	Global	Study-wide	5008	A=0.906	G=0.094
1000Genomes	South Asian	Sub	978	A=0.860	G=0.140
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.935	G=0.065
The Genome Aggregation Database	African	Sub	8724	A=0.959	G=0.041
The Genome Aggregation Database	American	Sub	838	A=0.930	G=0.070
The Genome Aggregation Database	East Asian	Sub	1622	A=0.900	G=0.100
The Genome Aggregation Database	Europe	Sub	18478	A=0.920	G=0.079
The Genome Aggregation Database	Global	Study-wide	29964	A=0.929	G=0.070
The Genome Aggregation Database	Other	Sub	302	A=0.750	G=0.250
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.929	G=0.070
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.927	G=0.073

PMID	Title	Author	Journal
21529783	A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.	Heath AC	Biol Psychiatry

SNP ID	p-value	Traits	Study
rs16834223	4.2E-05	alcoholism (heaviness of drinking)	21529783

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	137161799	137161998	E070	-32438
chr2	137162077	137162121	E070	-32315
chr2	137162459	137162513	E070	-31923
chr2	137164507	137164566	E070	-29870
chr2	137164613	137165030	E070	-29406
chr2	137165210	137165776	E070	-28660
chr2	137166799	137166849	E070	-27587
chr2	137199698	137199811	E070	5262
chr2	137200022	137200210	E070	5586
chr2	137200546	137200620	E070	6110
chr2	137199698	137199811	E071	5262
chr2	137164613	137165030	E081	-29406
chr2	137165210	137165776	E081	-28660

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	137181038	137181523	E067	-12913
chr2	137180934	137181034	E068	-13402
chr2	137181038	137181523	E068	-12913
chr2	137181551	137181658	E068	-12778
chr2	137181038	137181523	E069	-12913
chr2	137181551	137181658	E069	-12778
chr2	137181038	137181523	E070	-12913
chr2	137181551	137181658	E070	-12778
chr2	137181038	137181523	E071	-12913
chr2	137181038	137181523	E072	-12913
chr2	137181551	137181658	E072	-12778
chr2	137181038	137181523	E073	-12913
chr2	137181038	137181523	E074	-12913
chr2	137181551	137181658	E074	-12778
chr2	137180934	137181034	E082	-13402
chr2	137181038	137181523	E082	-12913
chr2	137181551	137181658	E082	-12778

rs16834223