rs16834223

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0070 (2120/29964,GnomAD)
G=0070 (2040/29118,TOPMED)
G=0094 (470/5008,1000G)
G=0065 (250/3854,ALSPAC)
G=0073 (270/3708,TWINSUK)
chr2:136436866 (GRCh38.p7) (2q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.136436866A>G
GRCh37.p13 chr 2NC_000002.11:g.137194436A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.950G=0.050
1000GenomesAmericanSub694A=0.930G=0.070
1000GenomesEast AsianSub1008A=0.893G=0.107
1000GenomesEuropeSub1006A=0.886G=0.114
1000GenomesGlobalStudy-wide5008A=0.906G=0.094
1000GenomesSouth AsianSub978A=0.860G=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.935G=0.065
The Genome Aggregation DatabaseAfricanSub8724A=0.959G=0.041
The Genome Aggregation DatabaseAmericanSub838A=0.930G=0.070
The Genome Aggregation DatabaseEast AsianSub1622A=0.900G=0.100
The Genome Aggregation DatabaseEuropeSub18478A=0.920G=0.079
The Genome Aggregation DatabaseGlobalStudy-wide29964A=0.929G=0.070
The Genome Aggregation DatabaseOtherSub302A=0.750G=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.929G=0.070
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.927G=0.073
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs168342234.2E-05alcoholism (heaviness of drinking)21529783

eQTL of rs16834223 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16834223 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2137161799137161998E070-32438
chr2137162077137162121E070-32315
chr2137162459137162513E070-31923
chr2137164507137164566E070-29870
chr2137164613137165030E070-29406
chr2137165210137165776E070-28660
chr2137166799137166849E070-27587
chr2137199698137199811E0705262
chr2137200022137200210E0705586
chr2137200546137200620E0706110
chr2137199698137199811E0715262
chr2137164613137165030E081-29406
chr2137165210137165776E081-28660



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2137181038137181523E067-12913
chr2137180934137181034E068-13402
chr2137181038137181523E068-12913
chr2137181551137181658E068-12778
chr2137181038137181523E069-12913
chr2137181551137181658E069-12778
chr2137181038137181523E070-12913
chr2137181551137181658E070-12778
chr2137181038137181523E071-12913
chr2137181038137181523E072-12913
chr2137181551137181658E072-12778
chr2137181038137181523E073-12913
chr2137181038137181523E074-12913
chr2137181551137181658E074-12778
chr2137180934137181034E082-13402
chr2137181038137181523E082-12913
chr2137181551137181658E082-12778