rs16836497

Homo sapiens
T>C
LOC101928306 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0197 (5918/29970,GnomAD)
C=0203 (5923/29118,TOPMED)
C=0190 (954/5008,1000G)
C=0210 (809/3854,ALSPAC)
C=0196 (725/3708,TWINSUK)
chr4:4950950 (GRCh38.p7) (4p16.2)
AD
GWASdb2
1   publication(s)
See rs on genome
56 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.4950950T>C
GRCh37.p13 chr 4NC_000004.11:g.4952677T>C

Gene: LOC101928306, uncharacterized LOC101928306(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101928306 transcriptNR_125893.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.797C=0.203
1000GenomesAmericanSub694T=0.740C=0.260
1000GenomesEast AsianSub1008T=0.774C=0.226
1000GenomesEuropeSub1006T=0.817C=0.183
1000GenomesGlobalStudy-wide5008T=0.810C=0.190
1000GenomesSouth AsianSub978T=0.910C=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.790C=0.210
The Genome Aggregation DatabaseAfricanSub8724T=0.800C=0.200
The Genome Aggregation DatabaseAmericanSub838T=0.720C=0.280
The Genome Aggregation DatabaseEast AsianSub1622T=0.756C=0.244
The Genome Aggregation DatabaseEuropeSub18484T=0.811C=0.188
The Genome Aggregation DatabaseGlobalStudy-wide29970T=0.802C=0.197
The Genome Aggregation DatabaseOtherSub302T=0.820C=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.796C=0.203
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.804C=0.196
PMID Title Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chen XDChin Med J (Engl)

P-Value

SNP ID p-value Traits Study
rs168364977.46E-05alcohol consumption22613542

eQTL of rs16836497 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16836497 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr449520864952253E067-424
chr449523804952651E067-26
chr449527294953211E06752
chr449968834997299E06844206
chr449454074946213E069-6464
chr449520864952253E069-424
chr449523804952651E069-26
chr449527294953211E06952
chr449923254993493E06939648
chr449520864952253E070-424
chr449523804952651E070-26
chr449527294953211E07052
chr449536274953677E070950
chr449968834997299E07044206
chr449974934997543E07044816
chr449976724997916E07044995
chr449520864952253E071-424
chr449523804952651E071-26
chr449527294953211E07152
chr449923254993493E07139648
chr449967714996882E07144094
chr449968834997299E07144206
chr449527294953211E07252
chr449923254993493E07239648
chr449968834997299E07244206
chr449974934997543E07244816
chr449520864952253E073-424
chr449523804952651E073-26
chr449527294953211E07352
chr449968834997299E07344206
chr449974934997543E07344816
chr449148594915598E081-37079
chr449159104916061E081-36616
chr449162424916389E081-36288
chr449165584916778E081-35899
chr449454074946213E081-6464
chr449463914946578E081-6099
chr449523804952651E081-26
chr449527294953211E08152
chr449536274953677E081950
chr449968834997299E08144206
chr449974934997543E08144816
chr449976724997916E08144995
chr449454074946213E082-6464
chr449523804952651E082-26
chr449541064954156E0821429
chr449823964982516E08229719
chr449826224982794E08229945
chr449828034983001E08230126
chr449830404983139E08230363
chr449832504983438E08230573
chr449834694983525E08230792
chr449967714996882E08244094
chr449968834997299E08244206
chr449974934997543E08244816
chr449976724997916E08244995