rs16843001

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0076 (2292/29936,GnomAD)
C=0084 (2455/29118,TOPMED)
C=0107 (538/5008,1000G)
C=0037 (144/3854,ALSPAC)
C=0037 (136/3708,TWINSUK)
chr1:198404196 (GRCh38.p7) (1q31.3)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.198404196T>C
GRCh37.p13 chr 1NC_000001.10:g.198373326T>C
GRCh38.p7 chr 1 alt locus HSCHR1_3_CTG31NW_003315907.2:g.34114T>C
GRCh37.p13 chr 1 novel patch HSCHR1_3_CTG31NW_003315907.1:g.34114T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.886C=0.114
1000GenomesAmericanSub694T=0.880C=0.120
1000GenomesEast AsianSub1008T=0.834C=0.166
1000GenomesEuropeSub1006T=0.960C=0.040
1000GenomesGlobalStudy-wide5008T=0.893C=0.107
1000GenomesSouth AsianSub978T=0.900C=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.963C=0.037
The Genome Aggregation DatabaseAfricanSub8720T=0.886C=0.114
The Genome Aggregation DatabaseAmericanSub836T=0.810C=0.190
The Genome Aggregation DatabaseEast AsianSub1612T=0.862C=0.138
The Genome Aggregation DatabaseEuropeSub18466T=0.951C=0.048
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.923C=0.076
The Genome Aggregation DatabaseOtherSub302T=0.960C=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.915C=0.084
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.963C=0.037
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs168430010.000221nicotine dependence17158188

eQTL of rs16843001 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16843001 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.