rs16846607

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0084 (2514/29888,GnomAD)
C=0102 (2978/29118,TOPMED)
C=0135 (675/5008,1000G)
C=0090 (347/3854,ALSPAC)
C=0091 (339/3708,TWINSUK)
chr3:103685267 (GRCh38.p7) (3q13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.103685267T>C
GRCh37.p13 chr 3NC_000003.11:g.103404111T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.923C=0.077
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.744C=0.256
1000GenomesEuropeSub1006T=0.917C=0.083
1000GenomesGlobalStudy-wide5008T=0.865C=0.135
1000GenomesSouth AsianSub978T=0.830C=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.910C=0.090
The Genome Aggregation DatabaseAfricanSub8724T=0.919C=0.081
The Genome Aggregation DatabaseAmericanSub834T=0.910C=0.090
The Genome Aggregation DatabaseEast AsianSub1566T=0.737C=0.263
The Genome Aggregation DatabaseEuropeSub18462T=0.930C=0.069
The Genome Aggregation DatabaseGlobalStudy-wide29888T=0.915C=0.084
The Genome Aggregation DatabaseOtherSub302T=0.890C=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.897C=0.102
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.909C=0.091
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs168466070.000248alcohol consumption (maxi-drinks)24277619

eQTL of rs16846607 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16846607 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.