rs16849209

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0229 (6855/29868,GnomAD)
T=0252 (7360/29118,TOPMED)
T=0217 (1087/5008,1000G)
T=0228 (880/3854,ALSPAC)
T=0231 (858/3708,TWINSUK)
chr2:212746497 (GRCh38.p7) (2q34)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.212746497G>T
GRCh37.p13 chr 2NC_000002.11:g.213611221G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.730T=0.270
1000GenomesAmericanSub694G=0.800T=0.200
1000GenomesEast AsianSub1008G=0.760T=0.240
1000GenomesEuropeSub1006G=0.784T=0.216
1000GenomesGlobalStudy-wide5008G=0.783T=0.217
1000GenomesSouth AsianSub978G=0.870T=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.772T=0.228
The Genome Aggregation DatabaseAfricanSub8702G=0.736T=0.264
The Genome Aggregation DatabaseAmericanSub834G=0.750T=0.250
The Genome Aggregation DatabaseEast AsianSub1606G=0.747T=0.253
The Genome Aggregation DatabaseEuropeSub18424G=0.789T=0.210
The Genome Aggregation DatabaseGlobalStudy-wide29868G=0.770T=0.229
The Genome Aggregation DatabaseOtherSub302G=0.760T=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.747T=0.252
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.769T=0.231
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs168492090.0005alcohol dependence20201924

eQTL of rs16849209 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16849209 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2213576928213578250E068-32971
chr2213641773213642215E07130552