SNP Detail Info-rs16860281

Organism: Homo sapiens

Alleles: T>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0108 (3240/29962,GnomAD)
C=0132 (3871/29118,TOPMED)
C=0095 (474/5008,1000G)
C=0088 (341/3854,ALSPAC)
C=0091 (339/3708,TWINSUK)

Position: chr3:148277560 (GRCh38.p7) (3q24)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 7 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.148277560T>C
GRCh37.p13 chr 3	NC_000003.11:g.147995347T>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.757	C=0.243
1000Genomes	American	Sub	694	T=0.940	C=0.060
1000Genomes	East Asian	Sub	1008	T=0.999	C=0.001
1000Genomes	Europe	Sub	1006	T=0.921	C=0.079
1000Genomes	Global	Study-wide	5008	T=0.905	C=0.095
1000Genomes	South Asian	Sub	978	T=0.970	C=0.030
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.912	C=0.088
The Genome Aggregation Database	African	Sub	8718	T=0.799	C=0.201
The Genome Aggregation Database	American	Sub	838	T=0.930	C=0.070
The Genome Aggregation Database	East Asian	Sub	1620	T=0.999	C=0.001
The Genome Aggregation Database	Europe	Sub	18484	T=0.923	C=0.076
The Genome Aggregation Database	Global	Study-wide	29962	T=0.891	C=0.108
The Genome Aggregation Database	Other	Sub	302	T=0.930	C=0.070
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.867	C=0.132
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.909	C=0.091

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs16860281	7.34E-06	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr3	147987063	147988743	E069	-6604
chr3	147987063	147988743	E071	-6604
chr3	147987063	147988743	E072	-6604
chr3	147947105	147947165	E074	-48182
chr3	147983419	147983655	E074	-11692
chr3	147983693	147983967	E074	-11380
chr3	147987063	147988743	E074	-6604

rs16860281