rs16868701

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0074 (2235/29964,GnomAD)
A=0117 (3430/29118,TOPMED)
A=0082 (413/5008,1000G)
A=0001 (4/3854,ALSPAC)
A=0002 (6/3708,TWINSUK)
chr5:964135 (GRCh38.p7) (5p15.33)
AD
GWASdb2
1   publication(s)
See rs on genome
59 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.964135G>A
GRCh37.p13 chr 5NC_000005.9:g.964250G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.704A=0.296
1000GenomesAmericanSub694G=0.970A=0.030
1000GenomesEast AsianSub1008G=1.000A=0.000
1000GenomesEuropeSub1006G=0.999A=0.001
1000GenomesGlobalStudy-wide5008G=0.918A=0.082
1000GenomesSouth AsianSub978G=1.000A=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.999A=0.001
The Genome Aggregation DatabaseAfricanSub8712G=0.748A=0.252
The Genome Aggregation DatabaseAmericanSub838G=0.990A=0.010
The Genome Aggregation DatabaseEast AsianSub1622G=1.000A=0.000
The Genome Aggregation DatabaseEuropeSub18490G=0.998A=0.001
The Genome Aggregation DatabaseGlobalStudy-wide29964G=0.925A=0.074
The Genome Aggregation DatabaseOtherSub302G=0.990A=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.882A=0.117
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.998A=0.002
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs168687010.000848alcohol dependence21314694

eQTL of rs16868701 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16868701 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5979613979688E06715363
chr5980275980403E06716025
chr5980416980643E06716166
chr5990036990692E06725786
chr5990786990869E06726536
chr5956860958334E068-5916
chr5990036990692E06825786
chr5990786990869E06826536
chr5990908991017E06826658
chr5980275980403E06916025
chr5980416980643E06916166
chr5980647980748E06916397
chr5956860958334E070-5916
chr5978177978325E07013927
chr5980275980403E07016025
chr5980416980643E07016166
chr5996924997531E07032674
chr5956860958334E071-5916
chr5958663959547E071-4703
chr5959588959628E071-4622
chr5980275980403E07116025
chr5980416980643E07116166
chr5980647980748E07116397
chr5980917980987E07116667
chr5990036990692E07125786
chr5990786990869E07126536
chr5990908991017E07126658
chr5996924997531E07132674
chr5945441945624E072-18626
chr5978177978325E07213927
chr5978400978552E07214150
chr5979333979383E07215083
chr5979613979688E07215363
chr5980275980403E07216025
chr5980416980643E07216166
chr5978400978552E07314150
chr5978620979032E07314370
chr5979333979383E07315083
chr5962246962298E074-1952
chr5980275980403E07416025
chr5980416980643E07416166
chr5980647980748E07416397
chr5980917980987E07416667
chr5981111981531E07416861
chr5990036990692E07425786
chr5990786990869E07426536
chr5966242966333E0811992
chr5966555966628E0812305
chr5968140968190E0813890
chr5968681968744E0814431
chr5969057969125E0814807
chr5980416980643E08116166
chr5980647980748E08116397
chr5966242966333E0821992
chr5966555966628E0822305
chr5968681968744E0824431
chr5969057969125E0824807
chr5978177978325E08213927
chr5978400978552E08214150










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr510045921005445E06740342
chr510098961009979E06745646
chr5926720927394E068-36856
chr510045921005445E06840342
chr510045921005445E06940342
chr510094941009625E06945244
chr510098961009979E06945646
chr5926720927394E070-36856
chr510045921005445E07040342
chr510090711009182E07044821
chr510092771009330E07045027
chr510093441009421E07045094
chr510098961009979E07045646
chr510045921005445E07140342
chr510090711009182E07144821
chr510092771009330E07145027
chr5926720927394E073-36856
chr510045921005445E07340342
chr510093441009421E07345094
chr510094941009625E07345244
chr5926720927394E074-36856
chr510045921005445E07440342
chr5926720927394E082-36856
chr510045921005445E08240342
chr510090711009182E08244821
chr510092771009330E08245027
chr510093441009421E08245094
chr510094941009625E08245244
chr510098961009979E08245646