rs168700

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0277 (8298/29902,GnomAD)
A=0298 (8685/29118,TOPMED)
A=0393 (1967/5008,1000G)
A=0204 (788/3854,ALSPAC)
A=0193 (714/3708,TWINSUK)
chr5:151239441 (GRCh38.p7) (5q33.1)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.151239441G>A
GRCh37.p13 chr 5NC_000005.9:g.150619002G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.644A=0.356
1000GenomesAmericanSub694G=0.740A=0.260
1000GenomesEast AsianSub1008G=0.433A=0.567
1000GenomesEuropeSub1006G=0.790A=0.210
1000GenomesGlobalStudy-wide5008G=0.607A=0.393
1000GenomesSouth AsianSub978G=0.460A=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.796A=0.204
The Genome Aggregation DatabaseAfricanSub8698G=0.651A=0.349
The Genome Aggregation DatabaseAmericanSub832G=0.710A=0.290
The Genome Aggregation DatabaseEast AsianSub1614G=0.419A=0.581
The Genome Aggregation DatabaseEuropeSub18456G=0.782A=0.217
The Genome Aggregation DatabaseGlobalStudy-wide29902G=0.722A=0.277
The Genome Aggregation DatabaseOtherSub302G=0.790A=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.701A=0.298
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.807A=0.193
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs1687000.000805alcohol dependence20201924

eQTL of rs168700 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs168700 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5150634078150634436E06715076
chr5150587953150588516E068-30486
chr5150618702150619282E0680
chr5150619301150619497E068299
chr5150634078150634436E06815076
chr5150604271150604321E069-14681
chr5150618702150619282E0690
chr5150619301150619497E069299
chr5150634078150634436E06915076
chr5150634496150634575E06915494
chr5150634720150634841E06915718
chr5150634966150635051E06915964
chr5150635064150635169E06916062
chr5150634078150634436E07115076
chr5150634496150634575E07115494
chr5150634720150634841E07115718
chr5150634966150635051E07115964
chr5150635064150635169E07116062
chr5150635316150635759E07116314
chr5150636282150636351E07117280
chr5150636468150636890E07117466
chr5150634078150634436E07315076
chr5150634496150634575E07315494
chr5150634078150634436E07415076
chr5150634496150634575E07415494
chr5150634720150634841E07415718
chr5150634966150635051E07415964
chr5150635064150635169E07416062






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5150602216150604193E067-14809
chr5150631538150633561E06712536
chr5150602216150604193E068-14809
chr5150631538150633561E06812536
chr5150602216150604193E069-14809
chr5150631538150633561E06912536
chr5150602216150604193E070-14809
chr5150631538150633561E07012536
chr5150602216150604193E071-14809
chr5150631538150633561E07112536
chr5150602216150604193E072-14809
chr5150631538150633561E07212536
chr5150602216150604193E073-14809
chr5150631538150633561E07312536
chr5150602216150604193E074-14809
chr5150631538150633561E07412536
chr5150631538150633561E08112536
chr5150602216150604193E082-14809
chr5150631538150633561E08212536