rs16870132

Homo sapiens
T>A / T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0133 (3987/29916,GnomAD)
C=0192 (5603/29118,TOPMED)
C=0162 (811/5008,1000G)
C=0020 (77/3854,ALSPAC)
C=0023 (85/3708,TWINSUK)
chr5:91848747 (GRCh38.p7) (5q14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.91848747T>A
GRCh38.p7 chr 5NC_000005.10:g.91848747T>C
GRCh37.p13 chr 5NC_000005.9:g.91144564T>A
GRCh37.p13 chr 5NC_000005.9:g.91144564T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.518C=0.482
1000GenomesAmericanSub694T=0.950C=0.050
1000GenomesEast AsianSub1008T=0.942C=0.058
1000GenomesEuropeSub1006T=0.980C=0.020
1000GenomesGlobalStudy-wide5008T=0.838C=0.162
1000GenomesSouth AsianSub978T=0.940C=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.980C=0.020
The Genome Aggregation DatabaseAfricanSub8688T=0.591A=0.001
The Genome Aggregation DatabaseAmericanSub836T=0.960A=0.00,
The Genome Aggregation DatabaseEast AsianSub1606T=0.943A=0.000
The Genome Aggregation DatabaseEuropeSub18484T=0.982A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29916T=0.866A=0.000
The Genome Aggregation DatabaseOtherSub302T=0.980A=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.807C=0.192
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.977C=0.023
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs168701320.00074alcohol dependence20201924

eQTL of rs16870132 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16870132 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr57305920273059307E070-48464
chr57305958273059773E070-47998
chr57310827573108346E082504
chr57310841373108574E082642


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr57310889373109572E0681122