rs16886113

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0081 (2455/29982,GnomAD)
G=0092 (2685/29118,TOPMED)
G=0101 (506/5008,1000G)
G=0077 (295/3854,ALSPAC)
G=0064 (237/3708,TWINSUK)
chr5:56699208 (GRCh38.p7) (5q11.2)
AD
GWASdb2
2   publication(s)
See rs on genome
47 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.56699208T>G
GRCh37.p13 chr 5NC_000005.9:g.55995035T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.875G=0.125
1000GenomesAmericanSub694T=0.930G=0.070
1000GenomesEast AsianSub1008T=0.861G=0.139
1000GenomesEuropeSub1006T=0.937G=0.063
1000GenomesGlobalStudy-wide5008T=0.899G=0.101
1000GenomesSouth AsianSub978T=0.910G=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.923G=0.077
The Genome Aggregation DatabaseAfricanSub8714T=0.885G=0.115
The Genome Aggregation DatabaseAmericanSub838T=0.950G=0.050
The Genome Aggregation DatabaseEast AsianSub1618T=0.871G=0.129
The Genome Aggregation DatabaseEuropeSub18510T=0.936G=0.063
The Genome Aggregation DatabaseGlobalStudy-wide29982T=0.918G=0.081
The Genome Aggregation DatabaseOtherSub302T=0.920G=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.907G=0.092
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.936G=0.064
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
27572337Association study confirms two susceptibility loci for breast cancer in Chinese Han women.Xu MBreast Cancer Res Treat

P-Value

SNP ID p-value Traits Study
rs168861130.00017alcohol dependence(early age of onset)20201924
rs168861130.00032alcohol dependence20201924

eQTL of rs16886113 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16886113 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55602936656029752E06734331
chr55602997556030570E06734940
chr55596482255964967E068-30068
chr55596498055965204E068-29831
chr55596535555965755E068-29280
chr55602997556030570E06834940
chr55603125456031353E06836219
chr55595585355956210E069-38825
chr55601311456013359E06918079
chr55601336756013537E06918332
chr55602936656029752E06934331
chr55602997556030570E06934940
chr55603125456031353E06936219
chr55600043056000528E0705395
chr55601025356010323E07015218
chr55601034056010403E07015305
chr55602997556030570E07034940
chr55603082056030870E07035785
chr55603125456031353E07036219
chr55595455855954648E071-40387
chr55595470755955182E071-39853
chr55596535555965755E071-29280
chr55596579455966296E071-28739
chr55599445055995756E0710
chr55601287156012985E07117836
chr55602997556030570E07134940
chr55603082056030870E07135785
chr55603181956032486E07136784
chr55596535555965755E072-29280
chr55601311456013359E07218079
chr55602997556030570E07234940
chr55599445055995756E0730
chr55602997556030570E07334940
chr55595455855954648E074-40387
chr55595470755955182E074-39853
chr55595585355956210E074-38825
chr55601311456013359E07418079
chr55602936656029752E07434331
chr55602997556030570E07434940
chr55603181956032486E07436784
chr55603261456032730E07437579
chr55599411555994372E081-663
chr55599445055995756E0810
chr55603181956032486E08136784
chr55603261456032730E08137579
chr55599445055995756E0820
chr55602997556030570E08234940