rs16897978

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0168 (5033/29912,GnomAD)
C==0181 (5275/29118,TOPMED)
C==0277 (1385/5008,1000G)
C==0066 (253/3854,ALSPAC)
C==0064 (237/3708,TWINSUK)
chr5:28696397 (GRCh38.p7) (5p14.1)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.28696397C>A
GRCh37.p13 chr 5NC_000005.9:g.28696504C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.319A=0.681
1000GenomesAmericanSub694C=0.180A=0.820
1000GenomesEast AsianSub1008C=0.635A=0.365
1000GenomesEuropeSub1006C=0.071A=0.929
1000GenomesGlobalStudy-wide5008C=0.277A=0.723
1000GenomesSouth AsianSub978C=0.130A=0.870
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.066A=0.934
The Genome Aggregation DatabaseAfricanSub8712C=0.298A=0.702
The Genome Aggregation DatabaseAmericanSub830C=0.150A=0.850
The Genome Aggregation DatabaseEast AsianSub1612C=0.583A=0.417
The Genome Aggregation DatabaseEuropeSub18458C=0.073A=0.926
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.168A=0.831
The Genome Aggregation DatabaseOtherSub300C=0.050A=0.950
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.181A=0.818
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.064A=0.936
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs168979785E-06alcohol dependence (age at onset)24962325

eQTL of rs16897978 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16897978 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.