rs16905611

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0118 (3536/29962,GnomAD)
C=0100 (2916/29118,TOPMED)
C=0165 (824/5008,1000G)
C=0136 (523/3854,ALSPAC)
C=0126 (466/3708,TWINSUK)
chr9:117419702 (GRCh38.p7) (9q33.1)
ND
GWASdb2
1   publication(s)
See rs on genome
254 Enhancers around
27 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.117419702A>C
GRCh37.p13 chr 9NC_000009.11:g.120181980A>C
ASTN2 RefSeqGeneNG_021409.1:g.338T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.992C=0.008
1000GenomesAmericanSub694A=0.690C=0.310
1000GenomesEast AsianSub1008A=0.688C=0.312
1000GenomesEuropeSub1006A=0.839C=0.161
1000GenomesGlobalStudy-wide5008A=0.835C=0.165
1000GenomesSouth AsianSub978A=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.864C=0.136
The Genome Aggregation DatabaseAfricanSub8728A=0.964C=0.036
The Genome Aggregation DatabaseAmericanSub834A=0.700C=0.300
The Genome Aggregation DatabaseEast AsianSub1612A=0.686C=0.314
The Genome Aggregation DatabaseEuropeSub18486A=0.868C=0.131
The Genome Aggregation DatabaseGlobalStudy-wide29962A=0.882C=0.118
The Genome Aggregation DatabaseOtherSub302A=0.890C=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.899C=0.100
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.874C=0.126
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs169056110.00058nicotine smoking19268276

eQTL of rs16905611 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16905611 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9120134507120134587E067-47393
chr9120136751120136854E067-45126
chr9120136949120136997E067-44983
chr9120137422120137472E067-44508
chr9120138614120138674E067-43306
chr9120139324120139766E067-42214
chr9120162348120162907E067-19073
chr9120163175120163235E067-18745
chr9120163475120163557E067-18423
chr9120165348120166415E067-15565
chr9120166480120166609E067-15371
chr9120166943120166993E067-14987
chr9120167196120167288E067-14692
chr9120167362120167412E067-14568
chr9120168231120168281E067-13699
chr9120168377120168489E067-13491
chr9120168596120168970E067-13010
chr9120169508120169619E067-12361
chr9120169925120169997E067-11983
chr9120170055120170291E067-11689
chr9120226093120226147E06744113
chr9120226344120226443E06744364
chr9120226686120226777E06744706
chr9120226931120226985E06744951
chr9120227329120227754E06745349
chr9120228085120228135E06746105
chr9120228218120228296E06746238
chr9120134507120134587E068-47393
chr9120136751120136854E068-45126
chr9120136949120136997E068-44983
chr9120137422120137472E068-44508
chr9120139324120139766E068-42214
chr9120163175120163235E068-18745
chr9120163475120163557E068-18423
chr9120166480120166609E068-15371
chr9120166943120166993E068-14987
chr9120167196120167288E068-14692
chr9120167362120167412E068-14568
chr9120168231120168281E068-13699
chr9120168377120168489E068-13491
chr9120168596120168970E068-13010
chr9120169508120169619E068-12361
chr9120169925120169997E068-11983
chr9120170055120170291E068-11689
chr9120173759120173871E068-8109
chr9120173881120174296E068-7684
chr9120179024120179149E068-2831
chr9120197522120197576E06815542
chr9120199675120199842E06817695
chr9120199876120200037E06817896
chr9120224469120224614E06842489
chr9120224826120224870E06842846
chr9120224876120225573E06842896
chr9120225829120225889E06843849
chr9120226093120226147E06844113
chr9120226344120226443E06844364
chr9120226686120226777E06844706
chr9120226931120226985E06844951
chr9120227329120227754E06845349
chr9120228085120228135E06846105
chr9120228218120228296E06846238
chr9120228524120228678E06846544
chr9120134507120134587E069-47393
chr9120135042120135136E069-46844
chr9120163175120163235E069-18745
chr9120163475120163557E069-18423
chr9120165348120166415E069-15565
chr9120166480120166609E069-15371
chr9120166943120166993E069-14987
chr9120167196120167288E069-14692
chr9120167362120167412E069-14568
chr9120168231120168281E069-13699
chr9120168377120168489E069-13491
chr9120168596120168970E069-13010
chr9120169508120169619E069-12361
chr9120169925120169997E069-11983
chr9120170055120170291E069-11689
chr9120224876120225573E06942896
chr9120225829120225889E06943849
chr9120226093120226147E06944113
chr9120226344120226443E06944364
chr9120226686120226777E06944706
chr9120226931120226985E06944951
chr9120227329120227754E06945349
chr9120228085120228135E06946105
chr9120228218120228296E06946238
chr9120228524120228678E06946544
chr9120134507120134587E070-47393
chr9120136751120136854E070-45126
chr9120136949120136997E070-44983
chr9120165348120166415E070-15565
chr9120199675120199842E07017695
chr9120199876120200037E07017896
chr9120205074120205165E07023094
chr9120205460120205549E07023480
chr9120205688120205776E07023708
chr9120205853120205994E07023873
chr9120222230120222369E07040250
chr9120224826120224870E07042846
chr9120224876120225573E07042896
chr9120225829120225889E07043849
chr9120226093120226147E07044113
chr9120226344120226443E07044364
chr9120226686120226777E07044706
chr9120226931120226985E07044951
chr9120227329120227754E07045349
chr9120228085120228135E07046105
chr9120228218120228296E07046238
chr9120228524120228678E07046544
chr9120134507120134587E071-47393
chr9120135042120135136E071-46844
chr9120135637120135692E071-46288
chr9120136751120136854E071-45126
chr9120136949120136997E071-44983
chr9120137422120137472E071-44508
chr9120138515120138555E071-43425
chr9120138614120138674E071-43306
chr9120139324120139766E071-42214
chr9120148025120148075E071-33905
chr9120148360120148420E071-33560
chr9120163475120163557E071-18423
chr9120165348120166415E071-15565
chr9120166480120166609E071-15371
chr9120166943120166993E071-14987
chr9120167196120167288E071-14692
chr9120167362120167412E071-14568
chr9120168231120168281E071-13699
chr9120168377120168489E071-13491
chr9120169508120169619E071-12361
chr9120169925120169997E071-11983
chr9120170055120170291E071-11689
chr9120173759120173871E071-8109
chr9120173881120174296E071-7684
chr9120224469120224614E07142489
chr9120224826120224870E07142846
chr9120224876120225573E07142896
chr9120225829120225889E07143849
chr9120226093120226147E07144113
chr9120226344120226443E07144364
chr9120226686120226777E07144706
chr9120226931120226985E07144951
chr9120227329120227754E07145349
chr9120228085120228135E07146105
chr9120228218120228296E07146238
chr9120228524120228678E07146544
chr9120134507120134587E072-47393
chr9120135637120135692E072-46288
chr9120136751120136854E072-45126
chr9120136949120136997E072-44983
chr9120137422120137472E072-44508
chr9120139324120139766E072-42214
chr9120148948120149035E072-32945
chr9120149167120149217E072-32763
chr9120162348120162907E072-19073
chr9120163175120163235E072-18745
chr9120163475120163557E072-18423
chr9120166480120166609E072-15371
chr9120166943120166993E072-14987
chr9120167196120167288E072-14692
chr9120167362120167412E072-14568
chr9120168231120168281E072-13699
chr9120168377120168489E072-13491
chr9120168596120168970E072-13010
chr9120169508120169619E072-12361
chr9120169925120169997E072-11983
chr9120170055120170291E072-11689
chr9120173759120173871E072-8109
chr9120173881120174296E072-7684
chr9120224876120225573E07242896
chr9120225829120225889E07243849
chr9120226093120226147E07244113
chr9120226686120226777E07244706
chr9120226931120226985E07244951
chr9120227329120227754E07245349
chr9120228085120228135E07246105
chr9120228218120228296E07246238
chr9120228524120228678E07246544
chr9120134507120134587E073-47393
chr9120165348120166415E073-15565
chr9120166480120166609E073-15371
chr9120166943120166993E073-14987
chr9120167196120167288E073-14692
chr9120167362120167412E073-14568
chr9120168231120168281E073-13699
chr9120168377120168489E073-13491
chr9120173759120173871E073-8109
chr9120173881120174296E073-7684
chr9120227329120227754E07345349
chr9120228085120228135E07346105
chr9120228218120228296E07346238
chr9120134507120134587E074-47393
chr9120135042120135136E074-46844
chr9120136751120136854E074-45126
chr9120136949120136997E074-44983
chr9120137422120137472E074-44508
chr9120138614120138674E074-43306
chr9120139324120139766E074-42214
chr9120162348120162907E074-19073
chr9120163175120163235E074-18745
chr9120163475120163557E074-18423
chr9120165348120166415E074-15565
chr9120166480120166609E074-15371
chr9120166943120166993E074-14987
chr9120167196120167288E074-14692
chr9120167362120167412E074-14568
chr9120168231120168281E074-13699
chr9120168377120168489E074-13491
chr9120168596120168970E074-13010
chr9120169508120169619E074-12361
chr9120169925120169997E074-11983
chr9120170055120170291E074-11689
chr9120173759120173871E074-8109
chr9120173881120174296E074-7684
chr9120179024120179149E074-2831
chr9120224469120224614E07442489
chr9120224826120224870E07442846
chr9120224876120225573E07442896
chr9120225829120225889E07443849
chr9120226093120226147E07444113
chr9120226344120226443E07444364
chr9120226686120226777E07444706
chr9120226931120226985E07444951
chr9120227329120227754E07445349
chr9120228085120228135E07446105
chr9120228218120228296E07446238
chr9120228524120228678E07446544
chr9120165348120166415E081-15565
chr9120168377120168489E081-13491
chr9120168596120168970E081-13010
chr9120169508120169619E081-12361
chr9120169925120169997E081-11983
chr9120170055120170291E081-11689
chr9120171753120171821E081-10159
chr9120173881120174296E081-7684
chr9120224469120224614E08142489
chr9120224826120224870E08142846
chr9120224876120225573E08142896
chr9120225829120225889E08143849
chr9120226093120226147E08144113
chr9120226344120226443E08144364
chr9120226686120226777E08144706
chr9120226931120226985E08144951
chr9120227329120227754E08145349
chr9120228085120228135E08146105
chr9120228218120228296E08146238
chr9120228524120228678E08146544
chr9120173881120174296E082-7684
chr9120199675120199842E08217695
chr9120199876120200037E08217896
chr9120226931120226985E08244951
chr9120227329120227754E08245349
chr9120228085120228135E08246105
chr9120228218120228296E08246238
chr9120228524120228678E08246544










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9120175287120175378E067-6602
chr9120175494120176375E067-5605
chr9120176389120177631E067-4349
chr9120175287120175378E068-6602
chr9120175494120176375E068-5605
chr9120176389120177631E068-4349
chr9120177639120178288E068-3692
chr9120175287120175378E069-6602
chr9120175494120176375E069-5605
chr9120176389120177631E069-4349
chr9120176389120177631E070-4349
chr9120175287120175378E071-6602
chr9120175494120176375E071-5605
chr9120176389120177631E071-4349
chr9120175287120175378E072-6602
chr9120175494120176375E072-5605
chr9120176389120177631E072-4349
chr9120177639120178288E072-3692
chr9120175287120175378E073-6602
chr9120175494120176375E073-5605
chr9120176389120177631E073-4349
chr9120177639120178288E073-3692
chr9120175287120175378E074-6602
chr9120175494120176375E074-5605
chr9120176389120177631E074-4349
chr9120176389120177631E082-4349
chr9120177639120178288E082-3692