SNP Detail Info-rs16905615

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0175 (5263/29950,GnomAD)
G==0231 (6753/29118,TOPMED)
G==0194 (971/5008,1000G)
G==0070 (271/3854,ALSPAC)
G==0069 (254/3708,TWINSUK)

Position: chr8:136315901 (GRCh38.p7) (8q24.23)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 5 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 8	NC_000008.11:g.136315901G>A
GRCh37.p13 chr 8	NC_000008.10:g.137328144G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.489	A=0.511
1000Genomes	American	Sub	694	G=0.120	A=0.880
1000Genomes	East Asian	Sub	1008	G=0.019	A=0.981
1000Genomes	Europe	Sub	1006	G=0.068	A=0.932
1000Genomes	Global	Study-wide	5008	G=0.194	A=0.806
1000Genomes	South Asian	Sub	978	G=0.160	A=0.840
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.070	A=0.930
The Genome Aggregation Database	African	Sub	8694	G=0.409	A=0.591
The Genome Aggregation Database	American	Sub	838	G=0.110	A=0.890
The Genome Aggregation Database	East Asian	Sub	1620	G=0.009	A=0.991
The Genome Aggregation Database	Europe	Sub	18496	G=0.084	A=0.915
The Genome Aggregation Database	Global	Study-wide	29950	G=0.175	A=0.824
The Genome Aggregation Database	Other	Sub	302	G=0.090	A=0.910
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.231	A=0.768
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.069	A=0.931

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs16905615	0.000411	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr8	137319447	137319631	E068	-8513
chr8	137308642	137309127	E081	-19017
chr8	137362145	137362205	E081	34001
chr8	137362258	137362318	E081	34114
chr8	137362518	137362704	E081	34374

rs16905615