rs16922195

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0182 (5431/29830,GnomAD)
G=0179 (5216/29118,TOPMED)
G=0188 (941/5008,1000G)
G=0173 (667/3854,ALSPAC)
G=0182 (675/3708,TWINSUK)
chr11:95559293 (GRCh38.p7) (11q21)
ND
GWASdb2
1   publication(s)
See rs on genome
81 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.95559293A>G
GRCh37.p13 chr 11NC_000011.9:g.95292457A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.840G=0.160
1000GenomesAmericanSub694A=0.610G=0.390
1000GenomesEast AsianSub1008A=0.833G=0.167
1000GenomesEuropeSub1006A=0.828G=0.172
1000GenomesGlobalStudy-wide5008A=0.812G=0.188
1000GenomesSouth AsianSub978A=0.880G=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.827G=0.173
The Genome Aggregation DatabaseAfricanSub8686A=0.851G=0.149
The Genome Aggregation DatabaseAmericanSub836A=0.610G=0.390
The Genome Aggregation DatabaseEast AsianSub1592A=0.786G=0.214
The Genome Aggregation DatabaseEuropeSub18414A=0.813G=0.186
The Genome Aggregation DatabaseGlobalStudy-wide29830A=0.817G=0.182
The Genome Aggregation DatabaseOtherSub302A=0.870G=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.820G=0.179
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.818G=0.182
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs169221950.000381nicotine dependence17158188

eQTL of rs16922195 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16922195 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr119530374695304096E06711289
chr119530419195304231E06711734
chr119530432895304396E06711871
chr119530515995305210E06712702
chr119530917495310091E06716717
chr119531013895310212E06717681
chr119534114795341259E06748690
chr119534134395341628E06748886
chr119525769895258226E068-34231
chr119528925495290498E068-1959
chr119529051995290667E068-1790
chr119529702695297411E0684569
chr119529742295297548E0684965
chr119529766995297853E0685212
chr119529882795299312E0686370
chr119529938995299798E0686932
chr119530303595303085E06810578
chr119530374695304096E06811289
chr119530515995305210E06812702
chr119530523395305273E06812776
chr119529702695297411E0694569
chr119529742295297548E0694965
chr119529766995297853E0695212
chr119529882795299312E0696370
chr119529938995299798E0696932
chr119530374695304096E06911289
chr119530419195304231E06911734
chr119530432895304396E06911871
chr119532547195326093E06933014
chr119532617495326284E06933717
chr119534009395340170E06947636
chr119534114795341259E06948690
chr119534134395341628E06948886
chr119529882795299312E0706370
chr119529938995299798E0706932
chr119528925495290498E071-1959
chr119529702695297411E0714569
chr119529742295297548E0714965
chr119529766995297853E0715212
chr119529882795299312E0716370
chr119529938995299798E0716932
chr119530419195304231E07111734
chr119530432895304396E07111871
chr119530515995305210E07112702
chr119530523395305273E07112776
chr119530917495310091E07116717
chr119531951395319857E07127056
chr119534114795341259E07148690
chr119534134395341628E07148886
chr119528709195287816E072-4641
chr119528925495290498E072-1959
chr119529742295297548E0724965
chr119529882795299312E0726370
chr119529938995299798E0726932
chr119530374695304096E07211289
chr119530419195304231E07211734
chr119530432895304396E07211871
chr119530515995305210E07212702
chr119530523395305273E07212776
chr119532368595323791E07231228
chr119532547195326093E07233014
chr119532617495326284E07233717
chr119534134395341628E07248886
chr119528925495290498E073-1959
chr119531013895310212E07317681
chr119532547195326093E07333014
chr119530515995305210E07412702
chr119530917495310091E07416717
chr119531013895310212E07417681
chr119531916895319473E07426711
chr119531951395319857E07427056
chr119534114795341259E07448690
chr119534134395341628E07448886
chr119528925495290498E081-1959
chr119529051995290667E081-1790
chr119529068695290795E081-1662
chr119529882795299312E0816370
chr119529938995299798E0816932
chr119530419195304231E08111734
chr119530432895304396E08111871
chr119528925495290498E082-1959