rs16925514

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0062 (1838/29634,GnomAD)
T=0079 (2309/29118,TOPMED)
T=0052 (260/5008,1000G)
T=0039 (151/3854,ALSPAC)
T=0039 (145/3708,TWINSUK)
chr11:34427713 (GRCh38.p7) (11p13)
AD
GWASdb2
2   publication(s)
See rs on genome
15 Enhancers around
16 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.34427713G>T
GRCh37.p13 chr 11NC_000011.9:g.34449260G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.868T=0.132
1000GenomesAmericanSub694G=0.960T=0.040
1000GenomesEast AsianSub1008G=1.000T=0.000
1000GenomesEuropeSub1006G=0.956T=0.044
1000GenomesGlobalStudy-wide5008G=0.948T=0.052
1000GenomesSouth AsianSub978G=0.980T=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.961T=0.039
The Genome Aggregation DatabaseAfricanSub8618G=0.879T=0.121
The Genome Aggregation DatabaseAmericanSub834G=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1616G=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18264G=0.959T=0.040
The Genome Aggregation DatabaseGlobalStudy-wide29634G=0.938T=0.062
The Genome Aggregation DatabaseOtherSub302G=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.920T=0.079
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.961T=0.039
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs169255140.0000668alcohol dependence21703634
rs169255140.0005alcohol dependence20201924

eQTL of rs16925514 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16925514 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr113446431934464369E06815059
chr113447611334476163E06826853
chr113447632034476483E06827060
chr113447658534477021E06827325
chr113442882134429256E069-20004
chr113442933034429448E069-19812
chr113446979334469875E06920533
chr113446994634470013E06920686
chr113442933034429448E071-19812
chr113442882134429256E072-20004
chr113442933034429448E072-19812
chr113446431934464369E07315059
chr113442882134429256E074-20004
chr113442933034429448E074-19812
chr113446252734462567E08213267







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr113445971234461758E06710452
chr113445957034459620E06810310
chr113445971234461758E06810452
chr113445957034459620E06910310
chr113445971234461758E06910452
chr113445957034459620E07010310
chr113445971234461758E07010452
chr113445971234461758E07110452
chr113445957034459620E07210310
chr113445971234461758E07210452
chr113445957034459620E07310310
chr113445971234461758E07310452
chr113445971234461758E07410452
chr113445971234461758E08110452
chr113445957034459620E08210310
chr113445971234461758E08210452