rs16936661

Homo sapiens
T>C
PRDM14 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0076 (2300/29980,GnomAD)
C=0114 (3339/29118,TOPMED)
C=0083 (414/5008,1000G)
C=0001 (2/3854,ALSPAC)
C=0000 (0/3708,TWINSUK)
chr8:70058383 (GRCh38.p7) (8q13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.70058383T>C
GRCh37.p13 chr 8NC_000008.10:g.70970618T>C

Gene: PRDM14, PR domain 14(minus strand)

Molecule type Change Amino acid[Codon] SO Term
PRDM14 transcriptNM_024504.3:c.N/AIntron Variant
PRDM14 transcript variant X1XM_011517572.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.698C=0.302
1000GenomesAmericanSub694T=0.980C=0.020
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=1.000C=0.000
1000GenomesGlobalStudy-wide5008T=0.917C=0.083
1000GenomesSouth AsianSub978T=1.000C=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.999C=0.001
The Genome Aggregation DatabaseAfricanSub8724T=0.739C=0.261
The Genome Aggregation DatabaseAmericanSub834T=0.990C=0.010
The Genome Aggregation DatabaseEast AsianSub1622T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18498T=0.999C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29980T=0.923C=0.076
The Genome Aggregation DatabaseOtherSub302T=1.000C=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.885C=0.114
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=1.000C=0.000
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs169366610.000273alcohol dependence21314694

eQTL of rs16936661 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16936661 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr87100119071001273E06730572
chr87094782170948112E071-22506
chr87100119071001273E07130572


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr87094728270947738E067-22880
chr87094656570947268E068-23350
chr87094728270947738E068-22880
chr87094728270947738E072-22880
chr87101266871012748E07442050
chr87101277671012927E07442158
chr87094656570947268E082-23350
chr87094728270947738E082-22880