rs16939329

Homo sapiens
G>A / G>C
ZFHX4-AS1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0185 (5559/29936,GnomAD)
C=0188 (5489/29118,TOPMED)
C=0194 (974/5008,1000G)
chr8:76651943 (GRCh38.p7) (8q21.13)
ND
GWASdb2
1   publication(s)
See rs on genome
146 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.76651943G>A
GRCh38.p7 chr 8NC_000008.11:g.76651943G>C
GRCh37.p13 chr 8NC_000008.10:g.77564178G>A
GRCh37.p13 chr 8NC_000008.10:g.77564178G>C

Gene: ZFHX4-AS1, ZFHX4 antisense RNA 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ZFHX4-AS1 transcriptNR_024360.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.741C=0.259
1000GenomesAmericanSub694G=0.880C=0.120
1000GenomesEast AsianSub1008G=0.820C=0.180
1000GenomesEuropeSub1006G=0.845C=0.155
1000GenomesGlobalStudy-wide5008G=0.806C=0.194
1000GenomesSouth AsianSub978G=0.790C=0.210
The Genome Aggregation DatabaseAfricanSub8710G=0.725C=0.275
The Genome Aggregation DatabaseAmericanSub838G=0.900C=0.100
The Genome Aggregation DatabaseEast AsianSub1614G=0.826C=0.174
The Genome Aggregation DatabaseEuropeSub18472G=0.851C=0.148
The Genome Aggregation DatabaseGlobalStudy-wide29936G=0.814C=0.185
The Genome Aggregation DatabaseOtherSub302G=0.830C=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.811C=0.188
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs169393290.000651nicotine dependence17158188

eQTL of rs16939329 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16939329 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8135634844135635155E067-19946
chr8135642388135642483E067-12618
chr8135642566135642677E067-12424
chr8135642749135642976E067-12125
chr8135642979135643029E067-12072
chr8135697167135698600E06742066
chr8135632109135632693E068-22408
chr8135632748135632829E068-22272
chr8135633003135633129E068-21972
chr8135633314135633364E068-21737
chr8135633429135633515E068-21586
chr8135634079135634816E068-20285
chr8135634844135635155E068-19946
chr8135642388135642483E068-12618
chr8135642566135642677E068-12424
chr8135642749135642976E068-12125
chr8135642979135643029E068-12072
chr8135643100135643341E068-11760
chr8135643398135643524E068-11577
chr8135651337135651428E068-3673
chr8135651469135651562E068-3539
chr8135651715135651785E068-3316
chr8135651818135651868E068-3233
chr8135651949135651999E068-3102
chr8135652045135652341E068-2760
chr8135652579135653445E068-1656
chr8135640173135640342E069-14759
chr8135655439135655979E069338
chr8135655990135656138E069889
chr8135656985135657065E0691884
chr8135701232135701314E06946131
chr8135701351135701401E06946250
chr8135701828135701903E06946727
chr8135701916135701961E06946815
chr8135703314135704044E06948213
chr8135647409135647515E070-7586
chr8135649058135649271E070-5830
chr8135649394135650037E070-5064
chr8135650161135650201E070-4900
chr8135650234135650471E070-4630
chr8135651818135651868E070-3233
chr8135651949135651999E070-3102
chr8135652045135652341E070-2760
chr8135652579135653445E070-1656
chr8135653576135653810E070-1291
chr8135656418135656616E0701317
chr8135676580135676630E07021479
chr8135676645135676704E07021544
chr8135676808135676879E07021707
chr8135677096135677182E07021995
chr8135699457135700332E07044356
chr8135701351135701401E07046250
chr8135701512135701614E07046411
chr8135701624135701710E07046523
chr8135701737135701790E07046636
chr8135632109135632693E071-22408
chr8135632748135632829E071-22272
chr8135642126135642252E071-12849
chr8135642388135642483E071-12618
chr8135642566135642677E071-12424
chr8135642749135642976E071-12125
chr8135642979135643029E071-12072
chr8135643100135643341E071-11760
chr8135643398135643524E071-11577
chr8135643588135644213E071-10888
chr8135703314135704044E07148213
chr8135703314135704044E07248213
chr8135632748135632829E073-22272
chr8135633003135633129E073-21972
chr8135643398135643524E073-11577
chr8135656985135657065E0731884
chr8135703314135704044E07348213
chr8135643100135643341E074-11760
chr8135643398135643524E074-11577
chr8135643588135644213E074-10888
chr8135611421135611570E081-43531
chr8135611699135612058E081-43043
chr8135618141135618243E081-36858
chr8135618294135618634E081-36467
chr8135622117135622531E081-32570
chr8135622571135622679E081-32422
chr8135622698135622769E081-32332
chr8135635601135635682E081-19419
chr8135635706135635756E081-19345
chr8135635769135635839E081-19262
chr8135636155135636229E081-18872
chr8135642566135642677E081-12424
chr8135642749135642976E081-12125
chr8135642979135643029E081-12072
chr8135643100135643341E081-11760
chr8135643398135643524E081-11577
chr8135643588135644213E081-10888
chr8135647409135647515E081-7586
chr8135651337135651428E081-3673
chr8135651469135651562E081-3539
chr8135651715135651785E081-3316
chr8135651818135651868E081-3233
chr8135651949135651999E081-3102
chr8135652045135652341E081-2760
chr8135652579135653445E081-1656
chr8135653576135653810E081-1291
chr8135653856135653905E081-1196
chr8135653979135654138E081-963
chr8135654314135654428E081-673
chr8135654783135654841E081-260
chr8135655161135655269E08160
chr8135656157135656239E0811056
chr8135656317135656367E0811216
chr8135697167135698600E08142066
chr8135698819135698997E08143718
chr8135699457135700332E08144356
chr8135700433135700514E08145332
chr8135609772135610012E082-45089
chr8135610063135610439E082-44662
chr8135615895135616087E082-39014
chr8135616228135616370E082-38731
chr8135616743135617260E082-37841
chr8135617291135617422E082-37679
chr8135617881135618065E082-37036
chr8135618141135618243E082-36858
chr8135618294135618634E082-36467
chr8135622117135622531E082-32570
chr8135622571135622679E082-32422
chr8135642126135642252E082-12849
chr8135642388135642483E082-12618
chr8135642566135642677E082-12424
chr8135642749135642976E082-12125
chr8135650161135650201E082-4900
chr8135651337135651428E082-3673
chr8135651469135651562E082-3539
chr8135651715135651785E082-3316
chr8135651818135651868E082-3233
chr8135651949135651999E082-3102
chr8135652045135652341E082-2760
chr8135652579135653445E082-1656
chr8135653576135653810E082-1291
chr8135653856135653905E082-1196
chr8135653979135654138E082-963
chr8135654314135654428E082-673
chr8135655161135655269E08260
chr8135655439135655979E082338
chr8135655990135656138E082889
chr8135656157135656239E0821056
chr8135656317135656367E0821216
chr8135656418135656616E0821317
chr8135656985135657065E0821884