rs16941404

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0171 (5139/29938,GnomAD)
G=0152 (4434/29118,TOPMED)
G=0166 (831/5008,1000G)
G=0205 (790/3854,ALSPAC)
G=0205 (759/3708,TWINSUK)
chr17:46976814 (GRCh38.p7) (17q21.32)
ND
GWASdb2
1   publication(s)
See rs on genome
118 Enhancers around
24 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.46976814C>G
GRCh37.p13 chr 17NC_000017.10:g.45054180C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.929G=0.071
1000GenomesAmericanSub694C=0.870G=0.130
1000GenomesEast AsianSub1008C=0.767G=0.233
1000GenomesEuropeSub1006C=0.761G=0.239
1000GenomesGlobalStudy-wide5008C=0.834G=0.166
1000GenomesSouth AsianSub978C=0.820G=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.795G=0.205
The Genome Aggregation DatabaseAfricanSub8714C=0.920G=0.080
The Genome Aggregation DatabaseAmericanSub836C=0.830G=0.170
The Genome Aggregation DatabaseEast AsianSub1614C=0.796G=0.204
The Genome Aggregation DatabaseEuropeSub18472C=0.787G=0.212
The Genome Aggregation DatabaseGlobalStudy-wide29938C=0.828G=0.171
The Genome Aggregation DatabaseOtherSub302C=0.860G=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.847G=0.152
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.795G=0.205
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs169414040.000243nicotine dependence17158188

eQTL of rs16941404 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16941404 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr174501793045018655E067-35525
chr174501985445021844E067-32336
chr174502665345026937E067-27243
chr174502697745027328E067-26852
chr174502740245027452E067-26728
chr174502777945028028E067-26152
chr174502826245028472E067-25708
chr174502853245028586E067-25594
chr174502966045029870E067-24310
chr174503432745034395E067-19785
chr174503530845035417E067-18763
chr174503561145035944E067-18236
chr174503604945036130E067-18050
chr174503632245036376E067-17804
chr174505724645057604E0673066
chr174508243845082550E06728258
chr174508269245082785E06728512
chr174508286445082949E06728684
chr174501366645013720E068-40460
chr174501379945013849E068-40331
chr174501985445021844E068-32336
chr174502229745022827E068-31353
chr174503530845035417E068-18763
chr174503561145035944E068-18236
chr174503604945036130E068-18050
chr174503632245036376E068-17804
chr174503652745036577E068-17603
chr174503667245036722E068-17458
chr174501985445021844E069-32336
chr174502777945028028E069-26152
chr174502826245028472E069-25708
chr174502853245028586E069-25594
chr174502866745028726E069-25454
chr174502876045028897E069-25283
chr174502893045029041E069-25139
chr174502915345029439E069-24741
chr174502966045029870E069-24310
chr174503530845035417E069-18763
chr174508077645080834E06926596
chr174508087745080920E06926697
chr174501985445021844E070-32336
chr174502853245028586E070-25594
chr174502866745028726E070-25454
chr174502876045028897E070-25283
chr174502893045029041E070-25139
chr174503530845035417E070-18763
chr174503561145035944E070-18236
chr174503604945036130E070-18050
chr174503632245036376E070-17804
chr174503652745036577E070-17603
chr174506368945064102E0709509
chr174506414245064227E0709962
chr174500744145007846E071-46334
chr174501985445021844E071-32336
chr174502893045029041E071-25139
chr174502915345029439E071-24741
chr174507837645079065E07124196
chr174508243845082550E07128258
chr174508269245082785E07128512
chr174508286445082949E07128684
chr174501793045018655E072-35525
chr174501985445021844E072-32336
chr174502229745022827E072-31353
chr174502826245028472E072-25708
chr174502853245028586E072-25594
chr174503530845035417E072-18763
chr174503561145035944E072-18236
chr174503632245036376E072-17804
chr174505243245052546E072-1634
chr174505283945052891E072-1289
chr174505296645053051E072-1129
chr174508286445082949E07228684
chr174501985445021844E073-32336
chr174502777945028028E073-26152
chr174502826245028472E073-25708
chr174502853245028586E073-25594
chr174503530845035417E073-18763
chr174503561145035944E073-18236
chr174503604945036130E073-18050
chr174503632245036376E073-17804
chr174503652745036577E073-17603
chr174501985445021844E074-32336
chr174505243245052546E074-1634
chr174508243845082550E07428258
chr174508269245082785E07428512
chr174508286445082949E07428684
chr174501985445021844E081-32336
chr174502826245028472E081-25708
chr174502853245028586E081-25594
chr174502866745028726E081-25454
chr174502876045028897E081-25283
chr174502893045029041E081-25139
chr174502915345029439E081-24741
chr174502966045029870E081-24310
chr174502995645030065E081-24115
chr174503432745034395E081-19785
chr174503442645034486E081-19694
chr174503530845035417E081-18763
chr174503561145035944E081-18236
chr174503604945036130E081-18050
chr174503632245036376E081-17804
chr174506368945064102E0819509
chr174506414245064227E0819962
chr174506425645064306E08110076
chr174502826245028472E082-25708
chr174502853245028586E082-25594
chr174502866745028726E082-25454
chr174502876045028897E082-25283
chr174502893045029041E082-25139
chr174503304445033098E082-21082
chr174503316845033237E082-20943
chr174503325745033357E082-20823
chr174503530845035417E082-18763
chr174503561145035944E082-18236
chr174503604945036130E082-18050
chr174503632245036376E082-17804
chr174504971645049768E082-4412
chr174505724645057604E0823066










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr174505565145055701E0671471
chr174505577745055956E0671597
chr174505597745056186E0671797
chr174505629645057089E0672116
chr174505565145055701E0681471
chr174505577745055956E0681597
chr174505597745056186E0681797
chr174505629645057089E0682116
chr174505565145055701E0691471
chr174505577745055956E0691597
chr174505629645057089E0692116
chr174505629645057089E0712116
chr174505565145055701E0721471
chr174505577745055956E0721597
chr174505629645057089E0722116
chr174505565145055701E0731471
chr174505577745055956E0731597
chr174505597745056186E0731797
chr174505629645057089E0732116
chr174505597745056186E0741797
chr174505629645057089E0742116
chr174505565145055701E0821471
chr174505597745056186E0821797
chr174505629645057089E0822116