rs16944011

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0066 (1991/29946,GnomAD)
G=0076 (2217/29118,TOPMED)
G=0060 (302/5008,1000G)
G=0066 (253/3854,ALSPAC)
G=0073 (271/3708,TWINSUK)
chr18:27712399 (GRCh38.p7) (18q12.1)
ND
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.27712399C>G
GRCh37.p13 chr 18NC_000018.9:g.25292363C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.900G=0.100
1000GenomesAmericanSub694C=0.930G=0.070
1000GenomesEast AsianSub1008C=0.936G=0.064
1000GenomesEuropeSub1006C=0.948G=0.052
1000GenomesGlobalStudy-wide5008C=0.940G=0.060
1000GenomesSouth AsianSub978C=0.990G=0.010
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.934G=0.066
The Genome Aggregation DatabaseAfricanSub8728C=0.913G=0.087
The Genome Aggregation DatabaseAmericanSub836C=0.950G=0.050
The Genome Aggregation DatabaseEast AsianSub1602C=0.959G=0.041
The Genome Aggregation DatabaseEuropeSub18480C=0.941G=0.058
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.933G=0.066
The Genome Aggregation DatabaseOtherSub300C=0.860G=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.923G=0.076
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.927G=0.073
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs169440119.74E-05nicotine smoking19268276

eQTL of rs16944011 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16944011 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr182530371625303813E06711353
chr182530399125304041E06711628
chr182524258625242707E069-49656
chr182529276425294322E070401
chr182532812725328188E07035764
chr182532841425328519E07036051
chr182532860325328653E07036240
chr182532874625328841E07036383
chr182532930025329466E07036937
chr182532957025329834E07037207
chr182532995925330311E07037596
chr182533037925330452E07038016
chr182533202525332075E07039662
chr182533233125332375E07039968
chr182533364125333691E07041278
chr182533377325333823E07041410
chr182534162625341723E07049263
chr182534211025342301E07049747
chr182524258625242707E072-49656
chr182529181925291945E082-418
chr182529198925292430E0820