rs16954296

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0226 (6793/29964,GnomAD)
T=0286 (8352/29118,TOPMED)
T=0227 (1139/5008,1000G)
T=0146 (561/3854,ALSPAC)
T=0146 (543/3708,TWINSUK)
chr15:70225369 (GRCh38.p7) (15q23)
AD
GWASdb2
1   publication(s)
See rs on genome
208 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.70225369C>T
GRCh37.p13 chr 15NC_000015.9:g.70517708C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.533T=0.467
1000GenomesAmericanSub694C=0.830T=0.170
1000GenomesEast AsianSub1008C=0.866T=0.134
1000GenomesEuropeSub1006C=0.823T=0.177
1000GenomesGlobalStudy-wide5008C=0.773T=0.227
1000GenomesSouth AsianSub978C=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.854T=0.146
The Genome Aggregation DatabaseAfricanSub8714C=0.576T=0.424
The Genome Aggregation DatabaseAmericanSub838C=0.820T=0.180
The Genome Aggregation DatabaseEast AsianSub1622C=0.837T=0.163
The Genome Aggregation DatabaseEuropeSub18488C=0.858T=0.141
The Genome Aggregation DatabaseGlobalStudy-wide29964C=0.773T=0.226
The Genome Aggregation DatabaseOtherSub302C=0.790T=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.713T=0.286
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.854T=0.146
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs169542960.00046alcohol dependence20201924

eQTL of rs16954296 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16954296 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr157048742670489875E067-27833
chr157055070570551997E06732997
chr157056215570563488E06744447
chr157056355670564605E06745848
chr157055070570551997E06832997
chr157055580370555942E06838095
chr157055602070556144E06838312
chr157055619470557134E06838486
chr157055975970560627E06842051
chr157056065570560793E06842947
chr157056081570561366E06843107
chr157056143870561575E06843730
chr157056163070562113E06843922
chr157056215570563488E06844447
chr157056355670564605E06845848
chr157056215570563488E06944447
chr157056355670564605E06945848
chr157047321270474223E070-43485
chr157048220170482415E070-35293
chr157048248870482810E070-34898
chr157048288970482996E070-34712
chr157048329370483702E070-34006
chr157048742670489875E070-27833
chr157048991370491066E070-26642
chr157049115970491213E070-26495
chr157049122270491568E070-26140
chr157049157770491679E070-26029
chr157049176270492539E070-25169
chr157049257170493823E070-23885
chr157049383370493988E070-23720
chr157049411570494198E070-23510
chr157049452570494579E070-23129
chr157049474270494816E070-22892
chr157049497170495139E070-22569
chr157049516070495210E070-22498
chr157049523070495352E070-22356
chr157049578170495884E070-21824
chr157050501670505091E070-12617
chr157050518070505562E070-12146
chr157050579170505841E070-11867
chr157050887170508921E070-8787
chr157050940470509594E070-8114
chr157051114670511266E070-6442
chr157051131570511444E070-6264
chr157051159470511913E070-5795
chr157051204270512126E070-5582
chr157051230670512385E070-5323
chr157051240470512464E070-5244
chr157051311070513418E070-4290
chr157051773670518033E07028
chr157051871070518890E0701002
chr157051892770518977E0701219
chr157051905970519124E0701351
chr157051913270519182E0701424
chr157054455470545243E07026846
chr157054532570545375E07027617
chr157055070570551997E07032997
chr157055200570552399E07034297
chr157055241970552727E07034711
chr157055274770552962E07035039
chr157055420370554253E07036495
chr157055435970554419E07036651
chr157055452370554638E07036815
chr157055466670554720E07036958
chr157055490870555047E07037200
chr157055511470555665E07037406
chr157055580370555942E07038095
chr157055602070556144E07038312
chr157055619470557134E07038486
chr157055713670557482E07039428
chr157055750770557601E07039799
chr157055763370557700E07039925
chr157055780570557990E07040097
chr157055800070558200E07040292
chr157055821970558317E07040511
chr157055839570558728E07040687
chr157055872970559617E07041021
chr157056143870561575E07043730
chr157056163070562113E07043922
chr157056215570563488E07044447
chr157056682370566897E07049115
chr157056694970567118E07049241
chr157048742670489875E071-27833
chr157054987670550686E07132168
chr157055070570551997E07132997
chr157055200570552399E07134297
chr157055511470555665E07137406
chr157055580370555942E07138095
chr157055602070556144E07138312
chr157055619470557134E07138486
chr157055713670557482E07139428
chr157055750770557601E07139799
chr157055763370557700E07139925
chr157055780570557990E07140097
chr157055800070558200E07140292
chr157055821970558317E07140511
chr157055839570558728E07140687
chr157055872970559617E07141021
chr157055975970560627E07142051
chr157056065570560793E07142947
chr157056081570561366E07143107
chr157056143870561575E07143730
chr157056163070562113E07143922
chr157056215570563488E07144447
chr157056355670564605E07145848
chr157048742670489875E072-27833
chr157055070570551997E07232997
chr157055800070558200E07240292
chr157055821970558317E07240511
chr157055839570558728E07240687
chr157055872970559617E07241021
chr157056355670564605E07245848
chr157048742670489875E073-27833
chr157055602070556144E07338312
chr157055872970559617E07341021
chr157056143870561575E07343730
chr157056163070562113E07343922
chr157056215570563488E07344447
chr157056355670564605E07345848
chr157048742670489875E074-27833
chr157055070570551997E07432997
chr157055200570552399E07434297
chr157055750770557601E07439799
chr157055763370557700E07439925
chr157055780570557990E07440097
chr157055800070558200E07440292
chr157055821970558317E07440511
chr157055839570558728E07440687
chr157055872970559617E07441021
chr157056163070562113E07443922
chr157056215570563488E07444447
chr157056355670564605E07445848
chr157047278670472860E081-44848
chr157047289170473002E081-44706
chr157047300670473111E081-44597
chr157047321270474223E081-43485
chr157048742670489875E081-27833
chr157048991370491066E081-26642
chr157049115970491213E081-26495
chr157049122270491568E081-26140
chr157049157770491679E081-26029
chr157049176270492539E081-25169
chr157049257170493823E081-23885
chr157049383370493988E081-23720
chr157049411570494198E081-23510
chr157049452570494579E081-23129
chr157049474270494816E081-22892
chr157049497170495139E081-22569
chr157049516070495210E081-22498
chr157049523070495352E081-22356
chr157049821870498274E081-19434
chr157049873170498803E081-18905
chr157049885970498933E081-18775
chr157049915270499313E081-18395
chr157050501670505091E081-12617
chr157050518070505562E081-12146
chr157054371870543935E08126010
chr157054393870544187E08126230
chr157054428170544478E08126573
chr157054455470545243E08126846
chr157054532570545375E08127617
chr157054545970545540E08127751
chr157054566470545769E08127956
chr157054606570546218E08128357
chr157054642270546538E08128714
chr157054661570547096E08128907
chr157054710170547212E08129393
chr157055070570551997E08132997
chr157055200570552399E08134297
chr157055602070556144E08138312
chr157055619470557134E08138486
chr157055872970559617E08141021
chr157056081570561366E08143107
chr157056143870561575E08143730
chr157056163070562113E08143922
chr157056215570563488E08144447
chr157047321270474223E082-43485
chr157048288970482996E082-34712
chr157048329370483702E082-34006
chr157049115970491213E082-26495
chr157049122270491568E082-26140
chr157049157770491679E082-26029
chr157049176270492539E082-25169
chr157049411570494198E082-23510
chr157049452570494579E082-23129
chr157049474270494816E082-22892
chr157049497170495139E082-22569
chr157049516070495210E082-22498
chr157050579170505841E082-11867
chr157051131570511444E082-6264
chr157051159470511913E082-5795
chr157054371870543935E08226010
chr157054393870544187E08226230
chr157054428170544478E08226573
chr157054455470545243E08226846
chr157054532570545375E08227617
chr157054545970545540E08227751
chr157055070570551997E08232997
chr157055200570552399E08234297
chr157055490870555047E08237200
chr157055511470555665E08237406
chr157055580370555942E08238095
chr157055602070556144E08238312
chr157055821970558317E08240511
chr157056081570561366E08243107
chr157056143870561575E08243730
chr157056163070562113E08243922
chr157056215570563488E08244447