rs16962759

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0119 (3575/29968,GnomAD)
C=0103 (3025/29118,TOPMED)
C=0098 (491/5008,1000G)
C=0133 (512/3854,ALSPAC)
C=0129 (479/3708,TWINSUK)
chr15:36256687 (GRCh38.p7) (15q14)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.36256687T>C
GRCh37.p13 chr 15NC_000015.9:g.36548888T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.927C=0.073
1000GenomesAmericanSub694T=0.920C=0.080
1000GenomesEast AsianSub1008T=0.912C=0.088
1000GenomesEuropeSub1006T=0.864C=0.136
1000GenomesGlobalStudy-wide5008T=0.902C=0.098
1000GenomesSouth AsianSub978T=0.890C=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.867C=0.133
The Genome Aggregation DatabaseAfricanSub8728T=0.927C=0.073
The Genome Aggregation DatabaseAmericanSub838T=0.900C=0.100
The Genome Aggregation DatabaseEast AsianSub1606T=0.899C=0.101
The Genome Aggregation DatabaseEuropeSub18494T=0.856C=0.143
The Genome Aggregation DatabaseGlobalStudy-wide29968T=0.880C=0.119
The Genome Aggregation DatabaseOtherSub302T=0.860C=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.896C=0.103
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.871C=0.129
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs169627590.0000638alcoholismpha002892
rs169627590.000064alcohol dependence(early age of onset)20201924
rs169627590.0000828alcoholismpha002893
rs169627590.000083alcohol dependence20201924

eQTL of rs16962759 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16962759 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr153654829036548437E067-451
chr153654857436548736E067-152
chr153654829036548437E069-451
chr153654857436548736E069-152
chr153654878536549060E0690
chr153659473636594823E07045848
chr153659498436595034E07046096
chr153659509336595143E07046205
chr153651121036511286E071-37602
chr153651129936511394E071-37494
chr153654829036548437E071-451
chr153654857436548736E071-152
chr153654857436548736E074-152
chr153654878536549060E0740
chr153659260036592670E08143712
chr153659275136593041E08143863
chr153659336236593454E08144474
chr153659418236594626E08145294
chr153659473636594823E08145848
chr153659498436595034E08146096
chr153659509336595143E08146205