rs16970282

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0327 (9798/29932,GnomAD)
C=0330 (9627/29118,TOPMED)
C=0350 (1751/5008,1000G)
C=0331 (1276/3854,ALSPAC)
C=0316 (1173/3708,TWINSUK)
chr17:34705079 (GRCh38.p7) (17q12)
AD
GWASdb2
1   publication(s)
See rs on genome
39 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.34705079A>C
GRCh37.p13 chr 17NC_000017.10:g.33032098A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.640C=0.360
1000GenomesAmericanSub694A=0.740C=0.260
1000GenomesEast AsianSub1008A=0.553C=0.447
1000GenomesEuropeSub1006A=0.674C=0.326
1000GenomesGlobalStudy-wide5008A=0.650C=0.350
1000GenomesSouth AsianSub978A=0.680C=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.669C=0.331
The Genome Aggregation DatabaseAfricanSub8718A=0.669C=0.331
The Genome Aggregation DatabaseAmericanSub838A=0.680C=0.320
The Genome Aggregation DatabaseEast AsianSub1614A=0.556C=0.444
The Genome Aggregation DatabaseEuropeSub18460A=0.683C=0.316
The Genome Aggregation DatabaseGlobalStudy-wide29932A=0.672C=0.327
The Genome Aggregation DatabaseOtherSub302A=0.740C=0.260
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.669C=0.330
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.684C=0.316
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs169702820.000335alcohol dependence21314694

eQTL of rs16970282 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16970282 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr173299466532994960E068-37138
chr173305216133052210E06820063
chr173305225233052336E06820154
chr173305287033053024E06820772
chr173299466532994960E069-37138
chr173299559632995740E069-36358
chr173298567332985723E070-46375
chr173298579632985836E070-46262
chr173298596832986491E070-45607
chr173303589233035979E0703794
chr173304090633040960E0708808
chr173304142233041513E0709324
chr173305183633051876E07019738
chr173305216133052210E07020063
chr173305225233052336E07020154
chr173305287033053024E07020772
chr173305578733055996E07023689
chr173305603233056280E07023934
chr173306666133066776E07034563
chr173306680533066872E07034707
chr173306707433067333E07034976
chr173306735533067424E07035257
chr173306746533068170E07035367
chr173306907533069190E07036977
chr173299466532994960E071-37138
chr173299466532994960E072-37138
chr173299466532994960E073-37138
chr173299466532994960E074-37138
chr173299559632995740E074-36358
chr173299214732993416E081-38682
chr173303791233037962E0815814
chr173303805133038105E0815953
chr173303873733038922E0816639
chr173303896233039015E0816864
chr173304090633040960E0818808
chr173306735533067424E08135257
chr173306746533068170E08135367
chr173298307532983231E082-48867
chr173299981632999866E082-32232