rs16981939

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0422 (12609/29838,GnomAD)
T==0468 (13627/29116,TOPMED)
T==0453 (2270/5008,1000G)
chr2:19177142 (GRCh38.p7) (2p24.1)
CD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.19177142T>C
GRCh37.p13 chr 2NC_000002.11:g.19376903T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.581C=0.419
1000GenomesAmericanSub694T=0.340C=0.660
1000GenomesEast AsianSub1008T=0.351C=0.649
1000GenomesEuropeSub1006T=0.340C=0.660
1000GenomesGlobalStudy-wide5008T=0.453C=0.547
1000GenomesSouth AsianSub978T=0.590C=0.410
The Genome Aggregation DatabaseAfricanSub8692T=0.559C=0.441
The Genome Aggregation DatabaseAmericanSub838T=0.330C=0.670
The Genome Aggregation DatabaseEast AsianSub1596T=0.355C=0.645
The Genome Aggregation DatabaseEuropeSub18410T=0.367C=0.633
The Genome Aggregation DatabaseGlobalStudy-wide29838T=0.422C=0.577
The Genome Aggregation DatabaseOtherSub302T=0.500C=0.500
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.468C=0.532
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs169819390.0000548cocaine dependence23958962
rs169819390.000555cocaine dependence23958962

eQTL of rs16981939 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16981939 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr21937803719378232E0671134
chr21937845019378507E0671547
chr21941657719416716E07039674
chr21941673119416917E07039828
chr21941711119417302E07040208
chr21939452319394985E08117620
chr21939522319395389E08118320
chr21939548219395724E08118579
chr21941604819416281E08139145
chr21941657719416716E08139674
chr21941673119416917E08139828
chr21941657719416716E08239674
chr21941673119416917E08239828