rs16985179

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0099 (2976/29966,GnomAD)
T=0120 (3519/29116,TOPMED)
T=0107 (534/5008,1000G)
T=0102 (394/3854,ALSPAC)
T=0095 (353/3708,TWINSUK)
chr22:27633571 (GRCh38.p7) (22q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
147 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 22NC_000022.11:g.27633571C>T
GRCh37.p13 chr 22NC_000022.10:g.28029538C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.864T=0.136
1000GenomesAmericanSub694C=0.910T=0.090
1000GenomesEast AsianSub1008C=0.904T=0.096
1000GenomesEuropeSub1006C=0.913T=0.087
1000GenomesGlobalStudy-wide5008C=0.893T=0.107
1000GenomesSouth AsianSub978C=0.890T=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.898T=0.102
The Genome Aggregation DatabaseAfricanSub8712C=0.874T=0.126
The Genome Aggregation DatabaseAmericanSub838C=0.930T=0.070
The Genome Aggregation DatabaseEast AsianSub1618C=0.897T=0.103
The Genome Aggregation DatabaseEuropeSub18496C=0.913T=0.086
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.900T=0.099
The Genome Aggregation DatabaseOtherSub302C=0.830T=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.879T=0.120
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.905T=0.095
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs169851796E-06alcohol consumption23743675

eQTL of rs16985179 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16985179 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr222803296128033498E0673423
chr222803352728033996E0673989
chr222803705228037648E0677514
chr222803765128037836E0678113
chr222803791328038837E0678375
chr222803894528039029E0679407
chr222803929428039400E0679756
chr222803944128039553E0679903
chr222803960328039682E06710065
chr222805836228060008E06728824
chr222806506828067932E06735530
chr222806892528069023E06739387
chr222806943328069483E06739895
chr222806950928069624E06739971
chr222806969428069803E06740156
chr222806981628070275E06740278
chr222807094628071087E06741408
chr222807564528075718E06746107
chr222803296128033498E0683423
chr222803352728033996E0683989
chr222803705228037648E0687514
chr222803765128037836E0688113
chr222803791328038837E0688375
chr222803894528039029E0689407
chr222806969428069803E06840156
chr222806981628070275E06840278
chr222807028028070544E06840742
chr222800539728005916E069-23622
chr222803296128033498E0693423
chr222803352728033996E0693989
chr222803405528034145E0694517
chr222803420928034309E0694671
chr222803434228034780E0694804
chr222803681328037040E0697275
chr222803705228037648E0697514
chr222803765128037836E0698113
chr222803791328038837E0698375
chr222803894528039029E0699407
chr222805056028050770E06921022
chr222805836228060008E06928824
chr222806506828067932E06935530
chr222806943328069483E06939895
chr222806950928069624E06939971
chr222806969428069803E06940156
chr222806981628070275E06940278
chr222807028028070544E06940742
chr222807059428070644E06941056
chr222798713727987318E070-42220
chr222798742627987511E070-42027
chr222798758527987639E070-41899
chr222798781027987872E070-41666
chr222798791127987961E070-41577
chr222798814127988318E070-41220
chr222799887227998922E070-30616
chr222799910427999201E070-30337
chr222799957128000075E070-29463
chr222800007828000144E070-29394
chr222805056028050770E07021022
chr222805080728051306E07021269
chr222806302928063712E07033491
chr222800521028005392E071-24146
chr222800539728005916E071-23622
chr222803296128033498E0713423
chr222803352728033996E0713989
chr222803405528034145E0714517
chr222803681328037040E0717275
chr222803705228037648E0717514
chr222803765128037836E0718113
chr222803791328038837E0718375
chr222803894528039029E0719407
chr222803929428039400E0719756
chr222805056028050770E07121022
chr222805080728051306E07121269
chr222806506828067932E07135530
chr222806858828068632E07139050
chr222806863528068675E07139097
chr222806878628068838E07139248
chr222806892528069023E07139387
chr222806917028069359E07139632
chr222806943328069483E07139895
chr222806950928069624E07139971
chr222806969428069803E07140156
chr222806981628070275E07140278
chr222807028028070544E07140742
chr222807059428070644E07141056
chr222807094628071087E07141408
chr222803241028032668E0722872
chr222803296128033498E0723423
chr222803681328037040E0727275
chr222803705228037648E0727514
chr222803765128037836E0728113
chr222803791328038837E0728375
chr222803894528039029E0729407
chr222805033928050390E07220801
chr222805056028050770E07221022
chr222805080728051306E07221269
chr222805836228060008E07228824
chr222806506828067932E07235530
chr222806845828068508E07238920
chr222806858828068632E07239050
chr222806863528068675E07239097
chr222806878628068838E07239248
chr222806892528069023E07239387
chr222806917028069359E07239632
chr222806943328069483E07239895
chr222806950928069624E07239971
chr222806969428069803E07240156
chr222806981628070275E07240278
chr222807028028070544E07240742
chr222807059428070644E07241056
chr222807094628071087E07241408
chr222807543628075571E07245898
chr222807564528075718E07246107
chr222807583228075969E07246294
chr222803705228037648E0737514
chr222803765128037836E0738113
chr222803791328038837E0738375
chr222803894528039029E0739407
chr222805836228060008E07328824
chr222806506828067932E07335530
chr222800539728005916E074-23622
chr222803296128033498E0743423
chr222803352728033996E0743989
chr222803681328037040E0747275
chr222803705228037648E0747514
chr222803765128037836E0748113
chr222803791328038837E0748375
chr222803894528039029E0749407
chr222805056028050770E07421022
chr222805080728051306E07421269
chr222805131828051488E07421780
chr222806506828067932E07435530
chr222806878628068838E07439248
chr222806892528069023E07439387
chr222806917028069359E07439632
chr222806943328069483E07439895
chr222806950928069624E07439971
chr222806969428069803E07440156
chr222806981628070275E07440278
chr222807028028070544E07440742
chr222807059428070644E07441056
chr222799910427999201E081-30337
chr222799957128000075E081-29463
chr222800007828000144E081-29394
chr222800974928009939E081-19599
chr222805056028050770E08121022
chr222805080728051306E08121269