rs16999432

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0085 (2553/29930,GnomAD)
T=0090 (2633/29118,TOPMED)
T=0075 (375/5008,1000G)
T=0060 (231/3854,ALSPAC)
T=0057 (212/3708,TWINSUK)
chr19:22589845 (GRCh38.p7) (19p12)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
49 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.22589845C>T
GRCh37.p13 chr 19NC_000019.9:g.22772647C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.889T=0.111
1000GenomesAmericanSub694C=0.950T=0.050
1000GenomesEast AsianSub1008C=0.934T=0.066
1000GenomesEuropeSub1006C=0.942T=0.058
1000GenomesGlobalStudy-wide5008C=0.925T=0.075
1000GenomesSouth AsianSub978C=0.930T=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.940T=0.060
The Genome Aggregation DatabaseAfricanSub8710C=0.884T=0.116
The Genome Aggregation DatabaseAmericanSub838C=0.980T=0.020
The Genome Aggregation DatabaseEast AsianSub1620C=0.952T=0.048
The Genome Aggregation DatabaseEuropeSub18460C=0.922T=0.077
The Genome Aggregation DatabaseGlobalStudy-wide29930C=0.914T=0.085
The Genome Aggregation DatabaseOtherSub302C=0.950T=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.909T=0.090
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.943T=0.057
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs169994329.23E-05alcohol consumption23953852

eQTL of rs16999432 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs16999432 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr192280414422804194E06831497
chr192280727522807315E06834628

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr192280622722806451E06733580
chr192280651322806574E06733866
chr192281644422816536E06743797
chr192281668422816741E06744037
chr192281677622817417E06744129
chr192281742722817548E06744780
chr192280622722806451E06833580
chr192280651322806574E06833866
chr192281644422816536E06843797
chr192281668422816741E06844037
chr192281677622817417E06844129
chr192281742722817548E06844780
chr192281770722817797E06845060
chr192280622722806451E06933580
chr192280651322806574E06933866
chr192281644422816536E06943797
chr192281668422816741E06944037
chr192281677622817417E06944129
chr192281742722817548E06944780
chr192281644422816536E07043797
chr192281668422816741E07044037
chr192281677622817417E07044129
chr192281742722817548E07044780
chr192281770722817797E07045060
chr192280622722806451E07133580
chr192280651322806574E07133866
chr192281644422816536E07143797
chr192281668422816741E07144037
chr192281677622817417E07144129
chr192281742722817548E07144780
chr192281644422816536E07243797
chr192281668422816741E07244037
chr192281677622817417E07244129
chr192281742722817548E07244780
chr192280651322806574E07333866
chr192281668422816741E07344037
chr192281677622817417E07344129
chr192281742722817548E07344780
chr192281677622817417E07444129
chr192281742722817548E07444780
chr192281644422816536E08143797
chr192281668422816741E08144037
chr192281677622817417E08144129
chr192281742722817548E08144780
chr192281644422816536E08243797
chr192281668422816741E08244037
chr192281677622817417E08244129
chr192281742722817548E08244780
chr192281770722817797E08245060